Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Potential feeding deterrents of Adelges tsugae found in biological control flies. [PDF]
Andrews O +3 more
europepmc +1 more source
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Molecular Mechanisms of the Biological Control of Pine Wilt Disease Using Microorganisms. [PDF]
Su X +6 more
europepmc +1 more source
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Modeling the Effect of the Biological Control of <i>Pseudococcus viburni</i> Signoret (Hemiptera: Pseudococcidae) on Grapevine Leafroll Virus Spread. [PDF]
Vogt-Geisse K +3 more
europepmc +1 more source
A review of non-microbial biological control strategies against the Asian longhorned beetle (Coleoptera: Cerambycidae). [PDF]
Johnson CL +7 more
europepmc +1 more source
Biological Control and Growth-Promoting Activities of Burkholderia vietnamiensis FBCC-B8049 Isolated from Freshwater. [PDF]
Han G, Cheon W, Heo Y, Lee CS.
europepmc +1 more source
Classical biological control of the brown marmorated stink bug (Halyomorpha halys) in apple orchard: a success story. [PDF]
Ioriatti C +9 more
europepmc +1 more source
DNA metabarcoding confirms Copsychus saularis, the common insectivorous species in oil palm plantations as biological control of ground-dwelling insect pests. [PDF]
Mustafa N, Yaakop S, Mohd-Taib FS.
europepmc +1 more source

