Results 101 to 110 of about 29,021,689 (318)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Development and evaluation of the recombinant BP26 protein-based C-ELISA for human brucellosis diagnosis

open access: yesFrontiers in Microbiology
IntroductionTimely and accurate diagnosis is crucial for the effective treatment and prevention of brucellosis. Current serological diagnostics, primarily based on lipopolysaccharide (LPS), suffer from cross-reactivity with other Gram-negative bacteria ...
Yujia Xie   +11 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1939

open access: yes, 1940
Annual report of the Marine Biological Laboratory in Woods Hole. 1939.
Marine Biological Laboratory (Woods Hole MA)
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Preparation and application of specific chicken yolk antibodies in detecting Brucella

open access: yesFrontiers in Veterinary Science
Brucellosis, caused by Brucella, is a severe zoonotic disease. Conventional IgG antibody-based ELISA testing faces challenges such as false positives and cross-reactivity.
Xinru Qi   +9 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1984

open access: yes, 1985
Annual report of the Marine Biological Laboratory in Woods Hole. 1984.
Marine Biological Laboratory (Woods Hole MA)
core  

Combinatorial Methods for biological Data.

open access: yes, 2021
Lo scopo di questa tesi è di elaborare e analizzare metodi rigorosi dal punto di vista matematico per l’analisi di due tipi di dati biologici: dati relativi a pan-genomi e filogenesi. Con il termine “pan-genoma” si indica, in generale, un insieme di sequenze genomiche strettamente correlate (tipicamente appartenenti a individui della stessa specie ...
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Medical Students’ Views on Cannabis Use in Recreational Contexts Are Related to Their Own Consumption Intention

open access: yesSocieties
Health professionals are regarded as important sources of information and guidance for healthy living. Knowing health determinants and risks, and invested with credibility in society, many struggle with their own human limits to apply these principles. A
Anca-Livia Panfil   +7 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1981

open access: yes, 1982
Annual report of the Marine Biological Laboratory in Woods Hole. 1981.
Marine Biological Laboratory (Woods Hole MA)
core  

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