Results 81 to 90 of about 29,021,689 (318)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1893
, 1894 Annual report of the Marine Biological Laboratory in Woods Hole. 1893.
Marine Biological Laboratory (Woods Hole MA)
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
A practical guide to methods controlling false discoveries in computational biology
Genome Biology, 2019 Background In high-throughput studies, hundreds to millions of hypotheses are typically tested. Statistical methods that control the false discovery rate (FDR) have emerged as popular and powerful tools for error rate control.
Keegan Korthauer +8 more
doaj +1 more source
Annual Report - Marine Biological Laboratory, 1903-1906
, 1907 https://hdl.handle.net/1912/21944Marine Biological Laboratory.
Marine Biological Laboratory (Woods Hole MA)
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1890
, 1890 Annual report of the Marine Biological Laboratory in Woods Hole. 1890.
Marine Biological Laboratory (Woods Hole MA)
core
Biological Knowledge Discovery and Data Mining
Scientific Programming, 2012 Mohammad Al Hasan a, Jun Huan b, Jake Chen c and Mohammed J. Zaki d a Department of Computer and Information Science, Indiana University–Purdue University, Indianapolis, IN, USA b Department of Electrical Engineering and Computer Science, University of Kansas, Lawrence, KS, USA c Indiana University School of Informatics, Indiana University–Purdue ...
Mohammad Al Hasan +3 more
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Ecotoxicology and Environmental SafetyRare earth elements are emerging environmental contaminants with potential neurological effects. Lanthanum (La), a widely used rare earth element, has drawn attention for its potential neurotoxicity.
Zhipeng Qi +12 more
doaj +1 more source