Results 71 to 80 of about 29,021,689 (318)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Warmer temperature accelerates senescence by modifying the aging-dependent changes in the mosquito transcriptome, altering immunity, metabolism, and DNA repair

open access: yesImmunity & Ageing
Background Global environmental temperatures are rising, which is increasing the body temperature of mosquitoes. This increase in body temperature is accelerating senescence, thereby weakening immune responses and reproductive processes, and shortening ...
Lindsay E. Martin   +5 more
doaj   +1 more source

Life cycle benzophenone 1 exposure induces anxiety- and depression-like behaviors in zebrafish via endoplasmic reticulum stress-mediated dopaminergic system dysfunction

open access: yesEnvironmental Chemistry and Ecotoxicology
Environmental exposure to benzophenones (BPs) has emerged as a potential risk factor for the comorbidity of anxiety and depression. Among them, BP1 has attracted increasing attention due to its potential neurotoxic effects.
Zhipeng Qi   +12 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1934

open access: yes, 1935
Annual report of the Marine Biological Laboratory in Woods Hole. 1934.
Marine Biological Laboratory (Woods Hole MA)
core  

Algorithms for biological sequence data

open access: yes, 2022
Sequences are a crucial concept in the bioinformatics field, as they can represent different kinds of biological data. Apart from the common string representations of DNA and protein sequences, many other kinds of biological data have an inherent sequential order.
openaire   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1929

open access: yes, 1930
Annual report of the Marine Biological Laboratory in Woods Hole. 1929.
Marine Biological Laboratory (Woods Hole MA)
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Development and evaluation of multiepitope fusion proteins for serological diagnosis of animal brucellosis

open access: yesMicrobiology Spectrum
Brucellosis, a zoonotic disease caused by Brucella spp., leads to severe reproductive issues in livestock and economic losses. Current serological diagnostics using lipopolysaccharide (LPS) antigens often exhibit cross-reactivity, reducing diagnostic ...
Liping Guo   +9 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1989

open access: yes, 1990
Annual report of the Marine Biological Laboratory in Woods Hole. 1989.
Marine Biological Laboratory (Woods Hole MA)
core  

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