Results 191 to 200 of about 29,021,689 (318)

A graph neural network model for inferring interindividual variation from experimental biological data. [PDF]

Sci Rep
Kawano F.
europepmc   +1 more source

Distilling identifiable and interpretable dynamic models from biological data. [PDF]

PLoS Comput Biol, 2023
Massonis G, Villaverde AF, Banga JR.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Editorial: Networks and graphs in biological data: current methods, opportunities and challenges. [PDF]

Front Bioinform
Thompson DL, Wu HY, Bartlett CW, Ray WC.
europepmc   +1 more source

MBDBMetrics: an online metrics tool to measure the impact of biological data resources. [PDF]

Bioinform Adv, 2023
Insana G, Ignatchenko A, Martin M, Bateman A, UniProt Consortium .   +4 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Enabling interpretable machine learning for biological data with reliability scores. [PDF]

PLoS Comput Biol, 2023
Ahlquist KD, Sugden LA, Ramachandran S.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Paediatric lymphoblastic lymphoma: a national review of 20 years of clinical and biological data in Ireland. [PDF]

Ann Hematol
Trinquand A, Betts DR, Rooney S, Storey L, McCarthy P, Barrett N, Bond J, O'Marcaigh A, Malone A, Smith OP.   +9 more
europepmc   +1 more source

The Genus Cynometra: A Review of Ethnomedicine, Chemical, and Biological Data. [PDF]

Plants (Basel), 2022
Sabiha S, Serrano R, Hasan K, Moreira da Silva IB, Rocha J, Islam N, Silva O.   +6 more
europepmc   +1 more source