Results 261 to 270 of about 29,021,689 (318)

Efficient Use of Biological Data in the Web 3.0 Era by Applying Nonfungible Token Technology. [PDF]

J Med Internet Res
Wang G, Chen C, Jiang Z, Li G, Wu C, Li S.   +5 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

List2Net: Linking multiple lists of biological data in a network context. [PDF]

Comput Struct Biotechnol J
Afxenti S, Tomazou M, Tsouloupas G, Lambrianides A, Pantzaris M, Spyrou GM.   +5 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

DataColor: unveiling biological data relationships through distinctive color mapping. [PDF]

Hortic Res
He S, Dong W, Chen J, Zhang J, Lin W, Yang S, Xu D, Zhou Y, Miao B, Wang W, Chen F.   +10 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

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Ontologies in Biological Data Visualization

IEEE Computer Graphics and Applications, 2014
In computer science, an ontology is essentially a graph-based knowledge representation in which each node corresponds to a concept and each edge specifies a relation between two concepts. Ontological development in biology can serve as a focus to discuss the challenges and possible research directions for ontologies in visualization.
Sheelagh Carpendale, Min Chen 0001, Daniel Evanko, Nils Gehlenborg, Carsten Görg, Lawrence Hunter, Francis Rowland, Margaret-Anne D. Storey, Hendrik Strobelt   +8 more
openaire   +2 more sources

From Biological Data to Biological Knowledge

2007
Large scale biological knowledge still organization remains a challenge in life sciences. Not only because related information is spread across several distributed information resources, but also because context dependent information retrieval suffers from an absence of semantic capabilities in biological databases.
Volker Stümpflen, Richard Gregory 0003, Karamfilka Nenova   +2 more
openaire   +1 more source

Biological Data Extinction

OMICS: A Journal of Integrative Biology, 2003
AS BIOINFORMATICIANS, we think of biological data in terms of an experiment and as a snapshot of some biological process. As such, we store and process large quantity of this data, and we seek to preserve the “sanctity of this data in perpetuity.” However, our users, the biologists, never look back at old data once they have reconciled the data by an ...
openaire   +3 more sources