Results 61 to 70 of about 259,966 (297)

Estimating dispersal distance in the deep sea: challenges and applications to marine reserves

Frontiers in Marine Science, 2015
Population connectivity refers to the exchange of individuals among populations: it affects gene flow, regulates population size and function, and mitigates recovery from natural or anthropogenic disturbances.
Ana eHilário, Anna eMetaxas, Sylvie eGaudron, Kerry eHowell, Annie eMercier, Nelia eMestre, Rebecca E Ross, Andreas eThurnherr, Craig eYoung   +8 more
doaj   +1 more source

Range expansion of an invasive species through a heterogeneous landscape - the case of American mink in Scotland [PDF]

, 2015
ACKNOWLEDGEMENTS We would like to thank Scottish Natural Heritage, particularly Iain Macleod and Rob Raynor, for data and funding.We are grateful to the Game and Wildlife Conservation Trust, especially Jonathan Reynolds, Vincent Wildlife Trust and ...
Aars, Aben, Allouche, Banks, Bocedi, Bonesi, Bryce, Craik, Cuthbert, Dunstone, Eskildsen, Fasola, Fraser, Freeman, Genovesi, Gerell, Getz, Gilbert, Gormley, Green, Green, Harrington, Hastings, Iordan, Jefferies, Jeschke, Kolbe, Lubina, Macdonald, Melero, Miller, Morgia, Nordström, Oliver, Peris, Rodrigues, Royle, Royle, Ruiz-Olmo, Sakai, Shigesada, Skellam, Strachan, Urban, Usher, White, With, Zalewski   +47 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Dispersal similarly shapes both population genetics and community patterns in the marine realm [PDF]

, 2016
Dispersal plays a key role to connect populations and, if limited, is one of the main processes to maintain and generate regional biodiversity. According to neutral theories of molecular evolution and biodiversity, dispersal limitation of propagules and ...
Bizsel, N., Bode, A., Borja, A., Broms, C., Chenuil, A., Chust, G., Claus, S., Fernández de Puelles, M.L., Fonda Umani, S., Hoarau, G., Irigoien, X., Mazzocchi, M.G., Mozetic, P., Vandepitte, L., Veríssimo, H., Villarino, E., Zervoudaki, S.   +16 more
core   +7 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

How Important Is Informed Natal Dispersal for Modelling the Demographic and Genetic Effects of Environmental Variability?

Ecology and Evolution
Dispersal is a fundamental ecological process that influences population dynamics and genetic diversity and is therefore an important component of the models used to simulate population responses to environmental change.
Sam C. Banks, Ian D. Davies, Teigan Cremona, Hugh F. Davies, Alexander R. Carey, Geoffrey J. Cary   +5 more
doaj   +1 more source

Gene flow and maintenance of genetic diversity in invasive mosquitofish (Gambusia holbrooki). [PDF]

PLoS ONE, 2013
Genetic analyses contribute to studies of biological invasions by mapping the origin and dispersal patterns of invasive species occupying new territories.
David Díez-del-Molino, Gerard Carmona-Catot, Rosa-Maria Araguas, Oriol Vidal, Nuria Sanz, Emili García-Berthou, Jose-Luis García-Marín   +6 more
doaj   +1 more source

Processes structuring macrophyte metacommunities in Mediterranean ponds: combining novel methods to disentangle the role of dispersal limitation, species sorting and spatial scales [PDF]

, 2019
Aim: Metacommunity ecology is a vibrant area of research that has received increased attention in recent years, since it provides a framework to assess the underlying dispersal- and niche-based processes that create non-random and ecologically meaningful
American Public Health Association, Castroviejo S, Cirujano S., Fernández‐Aláez C., García‐Girón J., Grimaldo J. T., Holyoak M., Junta de Castilla y León, R Core Team, Scheffer M.   +9 more
core   +1 more source