Results 31 to 40 of about 45,277 (259)

The importance of public health in radiology and radiation protection

Journal of Public Health Research, 2021
The ionizing radiation belongs to the basic physical factors that can be measured. We forget often about its risks and the possible damage to our health.
Zuzana Bárdyová, Martina Horváthová, Katarína Pinčáková, Darina Budošová   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An NMR-Based Metabolomics Study of Kidneys from Mice Exposed to Ionizing Radiation

Chinese Journal of Magnetic Resonance, 2019
The biological effects of ionizing radiation on organisms have emerged as a hot topic for research. In this study, the changes of metabolic profile in the kidney tissues extracts from C57BL/6J mice with or without exposing to whole body gamma or proton ...
XIAO Xiong-jie, HU Mary, ZHANG Xu, HU Jian-zhi   +3 more
doaj   +1 more source

The Role of Ionizing Radiation in Cellular Signaling Pathways, Mutagenesis, and Carcinogenesis [PDF]

International Journal of Basic Science in Medicine, 2018
One of the negative effects of ionizing radiation is the alteration of cellular signaling pathways which lead to carcinogenesis and tumorigenesis. In this review, we discussed the impacts of ionizing radiation on cells and cellular signaling pathways. In
Sakine Rezaie Kahkhaie, Khadije Rezaie Keikhaie   +1 more
doaj   +1 more source

Knowledge and comprehension about health risk and safe radiographic techniques among the dental students of Vivekanandha Dental College For Women – A cross-sectional study

Dentistry and Medical Research, 2023
Introduction: Ionizing radiation has biological health hazards. Increased level of ionizing radiation has both stochastic and deterministic effect. Aim: The aim of the current study was to evaluate the knowledge, approach, and insight of the biological ...
Jennifer Monisha Rajan, Kavya Ganesh Kamaraj, Girish R Shavi, Shankar Shanmugam, Senthil Kumar Sennan, Lalithambigai Gunasekaran   +5 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Involvement of GSTP1 in low dose radiation-induced apoptosis in GM12878 cells

Ecotoxicology and Environmental Safety
Background: Low-dose ionizing radiation-induced protection and damage are of great significance among radiation workers. We aimed to study the role of glutathione S-transferase Pi (GSTP1) in low-dose ionizing radiation damage and clarify the impact of ...
Jian Cui, Linwei Li, Shuang Wei, Yuanyun Wei, Yaqi Gong, Hongxia Yan, Yueqiu Yu, Xiang Lin, Hui Qin, Guoqing Li, Lan Yi   +10 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Evaluation of cytogenetic biomarkers in occupationally exposures of medical radiation-workers to low doses of ionizing radiation: A review article

Fiyz̤, 2022
Background: Ionizing radiation plays an important role in medical diagnosis and treatment. However, it may have adverse effects on human health. Adherence to the principles of protection against ionizing radiation can be effective in reducing these ...
Mousavikia SN, Bahreyni-Toossi MT, Khademi S, Azimian H   +3 more
doaj  

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source