Results 251 to 260 of about 2,108,914 (342)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Are All Species Created Equal? A Critique of the "Equal Fitness Paradigm". [PDF]

Biology (Basel)
Glazier DS.
europepmc   +1 more source

Biological efficiency of the laboratory samples of microbiopreparations based on the perspective strains-producers from species Chaetomium and Bacillus controlling downy mildew pathogen on sunflower

, 2019
Л.В. Маслиенко
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Comparative Evaluation of Automated Nucleic Acid Extraction Systems for DNA and RNA Viral Target. [PDF]

Pathogens
Treggiari D, Castilletti C, Nicolini L, Mazzi C, Perandin F, Formenti F.   +5 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Sub-50-femtosecond gain-managed amplified pulses enhance nonlinear ablation efficiency. [PDF]

Biomed Opt Express
Price LJ, Zhang K, Otero NJ, Repgen P, Valdes PA, Wise F, Ilday FÖ, Spring BQ.   +7 more
europepmc   +1 more source

Sinking particle fluxes and biological carbon pump efficiency in the Labrador Sea during a Phaeocystis bloom decline [PDF]

Montserrat Roca‐Martí, Madeline G. Healey, Colleen E. McBride, Rachel E. Sipler, Emmanuel Devred, Carolina Cisternas‐Novoa, Elisa Romanelli, Kyoko Ohashi, Markus Kienast   +8 more
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Substantial Limitations of Ocean Alkalinity Enhancement in Mitigating the Negative Impacts of Ocean Acidification on Marine Calcifiers. [PDF]

Environ Sci Technol
van de Mortel H, Bednaršek N, Pelletier G, Feely RA, Müller JD, Gruber N.   +5 more
europepmc   +1 more source