Results 121 to 130 of about 599,729 (261)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Smart CO₂ capture and release and an insight into biological evolution based on its characteristics. [PDF]

Sci Rep
Sorimachi K, Tsukada T.
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Transition Processes in Technological Systems: Inspiration from Processes in Biological Evolution. [PDF]

Biomimetics (Basel)
Möller M, Speck O, Thekkepat H, Speck T.   +3 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Cooperation and Competition Were Primary Driving Forces for Biological Evolution. [PDF]

Microb Physiol
Saier MH.
europepmc   +1 more source

How and why kinetics, thermodynamics, and chemistry induce the logic of biological evolution. [PDF]

Beilstein J Org Chem, 2017
Pross A, Pascal R.
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

The prebiotic emergence of biological evolution. [PDF]

R Soc Open Sci
Kocher CD, Dill KA.
europepmc   +1 more source

Chemical roots of biological evolution: the origins of life as a process of development of autonomous functional systems. [PDF]

Open Biol, 2017
Ruiz-Mirazo K, Briones C, de la Escosura A.   +2 more
europepmc   +1 more source