Results 101 to 110 of about 1,894,620 (286)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Ecology and EvolutionIn photoperiod sensitive plants, the timing of phenological events depends primarily on day length rather than temperature, precipitation or other environmental variables.
Ashika Perrin +5 more
doaj +1 more source
Teaching nature of science in introductory biology: Impacts on students' acceptance of biological evolution. [PDF]
PLoS One, 2023 Sloane JD, Wheeler LB, Manson JS.
europepmc +1 more source
Biological evolution and statistical physics [PDF]
Advances in Physics, 2001 This review is an introduction to theoretical models and mathematical calculations for biological evolution, aimed at physicists. The methods in the field are naturally very similar to those used in statistical physics, although the majority of publications appeared in biology journals. The review has three parts, which can be read independently.
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Mineral Element Insiders and Outliers Play Crucial Roles in Biological Evolution. [PDF]
Life (Basel), 2022 Moore EK +4 more
europepmc +1 more source
Asceticism, Religion, and Biological Evolution' [PDF]
Method & Theory in the Study of Religion, 2001 AbstractThis article initially argues that asceticism and related phenomena in classical India and in Christian antiquity suggest the existence of a universal, shared, innate human predisposition. After providing descriptive data on the widespread belief in a soul distinct from the body, along with cross-cultural accounts of ascetic practices, the ...
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Impact of Life Philosophy and Major Field of Study on Brazilian Students' Knowledge of Biological Evolution. [PDF]
Sci Educ (Dordr), 2023 Demetrio GR, Jacobina UP, Barão KR.
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source