Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Author Correction: Assessing the effect of wind farms in fauna with a mathematical model
Scientific Reports, 2021 Pablo Refoyo Román +2 more
doaj +1 more source
Annual Report - Marine Biological Laboratory, 1988
, 1989 Annual report of the Marine Biological Laboratory in Woods Hole. 1988.
Marine Biological Laboratory (Woods Hole MA)
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Biological evolution and human cognition are analogous information processing systems. [PDF]
Front Psychol, 2023 Castro-Alonso JC, Hidalgo AA, Sweller J.
europepmc +1 more source
Annual Report - Marine Biological Laboratory, 1935
, 1936 Annual report of the Marine Biological Laboratory in Woods Hole. 1935.
Marine Biological Laboratory (Woods Hole MA)
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Teaching nature of science in introductory biology: Impacts on students' acceptance of biological evolution. [PDF]
PLoS One, 2023 Sloane JD, Wheeler LB, Manson JS.
europepmc +1 more source
Annual Report - Marine Biological Laboratory, 1943
, 1944 Annual report of the Marine Biological Laboratory in Woods Hole. 1943.
Marine Biological Laboratory (Woods Hole MA)
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source