Results 91 to 100 of about 83,265 (261)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Taming of Evolution

open access: yes, 2018
The theory of evolution has clearly altered our views of the biological world, but in the study of human beings, evolutionary and preevolutionary views continue to coexist in a state of perpetual tension.
Greenwood, Davydd
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Whole-Genome Sequencing Analyses Reveal the Evolution Mechanisms of Typical Biological Features of Decapterus maruadsi

open access: yesAnimals
Decapterus maruadsi is a typical representative of small pelagic fish characterized by fast growth rate, small body size, and high fecundity. It is a high-quality marine commercial fish with high nutritional value.
Wen-Jian Deng   +6 more
doaj   +1 more source

Culture Outsmarts Nature in the Evolution of Cooperation [PDF]

open access: yes
A one dimensional cellular automata model describes the evolutionary dynamics of cooperation when grouping by cooperators provides protection against predation. It is used to compare the dynamics of evolution of cooperation in three settings.
Roberto Cipriani, Klaus Jaffe
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Axiological and epistemological contributions to teaching the theory of evolution Darwin [PDF]

open access: yesInvestigações em Ensino de Ciências, 2011
From the essential role of theme “biological evolution” in scientific formation of students and the diversity of issues identified in the literature for teaching of the same, we developed a qualitative study through contributions of Didactics of Science ...
Lucken Bueno Lucas   +1 more
doaj  

Knowledge of evolution and evolution of knowledge

open access: yes, 1981
It is argued that evolution goes beyond that which can be described in a well-defined language) and that it instead enforces a language that is itself evolving. Evolution is the unfolding of this self-reference.
Löfgren, Lars,, Lund University.
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Psychopathological Implications of Behavioral Patterns in Obsessive–Compulsive Rituals: A Hierarchical Analysis

open access: yesBrain Sciences
Background/Objectives: Compulsive rituals in Obsessive–Compulsive Disorder (OCD) are characterized by a specific motor structure, built upon the fragmentation of action flow, obtained through act repetitions and the intrusion of non-functional acts.
Luca Gambolò   +5 more
doaj   +1 more source

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