Results 161 to 170 of about 531,456 (310)
The virtue of innovation: innovation through the lenses of biological evolution. [PDF]
Kell DB, Lurie-Luke E.
europepmc +1 more source
Symbiosis in the Bak–Sneppen model for biological evolution with economic applications [PDF]
M. Bartolozzi+2 more
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Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
On quantum effects in a theory of biological evolution. [PDF]
Martin-Delgado MA.
europepmc +1 more source
Beware of Nuts & Bolts: Putting Evolution into the Teaching of Biological Classification [PDF]
Martin K. Nickels, Craig E. Nelson
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Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source
color categories in biological evolution: broadening the palette [PDF]
Wayne Christensen, Luca Tommasi
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This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
Modeling Intelligent Ontology Evolution Using Biological Evolutionary Processes [PDF]
Paul O’Brien, Syed Sibte Raza Abidi
openalex +1 more source