Results 21 to 30 of about 599,729 (261)

Cosmic Perspectives and the Myths We Need to Survive

Journal of Big History, 2019
Big history can be defined as the attempt to understand the integrated history of the cosmos, Earth, life and humanity. Cosmic perspectives and biological evolution are the main scientific ingredients that can convert and broaden history into big history.
Charles H. Lineweaver
doaj   +1 more source

Age structure landscapes emerge from the equilibrium between aging and rejuvenation in bacterial populations

Nature Communications, 2018
Some daughter cells inherit the maternal old pole during bacterial division, but does this correspond to aging? Here, Proenca et al. show that constant patterns of aging and rejuvenation connect distinct growth equilibria within bacterial clonal ...
Audrey M. Proenca, Camilla Ulla Rang, Christen Buetz, Chao Shi, Lin Chao   +4 more
doaj   +1 more source

Alone in the world? Indeed, and liberatingly so

Verbum et Ecclesia, 2021
How do we know that we can trust our viewpoints, our dogmatic principles and our religious convictions to constitute veracity, if not truth? Where can an arbiter be found for our deliberations to establish the trustworthiness of our viewpoints or belief ...
Barend J. du Toit
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Directed information panspermia as a possible method of interstellar communication

Frontiers in Astronomy and Space Sciences
The problem of transmitting an interstellar message from one communicative civilization to another is examined, taking into account possible scenarios for the prevalence of civilizations in the Galaxy, including the possibility that Earth’s civilization ...
Sh. M. Kocharyan
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European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille, Hugo Roux, Odile Fenneteau, Aurélie Caye‐Eude, Alexia Kinoo, Yoann Vial, André Baruchel, Marion Strullu, Elodie Lainey, Hélène Cavé   +9 more
wiley   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Satellite‐Derived NDVI Predicts Forage Availability in a Wild Ungulate System: Ground‐Truthing Using Field‐Collected Vegetation Biomass

Ecology and Evolution
Satellite‐derived vegetation indices provide a powerful means to quantify habitat variation in long‐term ecological studies, but their reliability as proxies for forage availability in wild herbivore populations remains underexplored.
Shane Butt, Kirsty Macphie, Richard S. Turner, Sean J. Morris, Alison Morris, Robin Pakeman, Loeske E. B. Kruuk, J. M. Pemberton, H. Froy   +8 more
doaj   +1 more source

Origin of Life: The Point of No Return

Life, 2020
Origin of life research is one of the greatest scientific frontiers of mankind. Many hypotheses have been proposed to explain how life began. Although different hypotheses emphasize different initial phenomena, all of them agree around one important ...
Dimiter Kunnev
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