Results 21 to 30 of about 405,367 (255)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Phragmites australis and Argyrogramma albostriata Suppress the Invasion of Solidago canadensis in China Under Future Climate Change

Ecology and Evolution
Global warming has significantly accelerated the invasion process and expanded the distribution range of Solidago canadensis. It forms a dominant monoculture in multiple regions via wind‐dispersed seeds and rhizome clonal propagation, posing a serious ...
Jinghui Zhang, Xiaoying Xiao, Wei Huang, Yuxin Huo, Yuxin Zhang, Shujian Zhang, Xinyi Huang, Muhammad Umair Hassan, Yuxi Xue, Qitao Su, Yian Xiao   +10 more
doaj   +1 more source

Transcriptome Analysis Revealed Potential Regulatory Networks Underlying Corolla Movement in Mirabilis jalapa (Nyctaginaceae)

Biology
Corolla movement is a typical plant movement behavior that enables plants to optimize pollination and adapt to environmental changes. Nevertheless, its molecular mechanism remains poorly understood.
Dingkun Liu, Huiqi Yan, Xuan Wang, Xiaohong Yan, Bing Zhou   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Spatio-Temporal Evolution of Ecological Network Resilience in the Poyang Lake Eco-Economic Zone from the Perspective of Complex Network Analysis

Biology
Ecological network resilience is an important indicator for evaluating whether regional ecosystems can maintain structural connectivity and functional stability under external disturbance.
Xinyi Huang, Sichen Wei, Wenkai Ding, Yian Xiao, Qitao Su   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Comparative study on the expression levels of antithrombotic genes in five sympatrically distributed leech species

BMC Genomics
Medicinal leeches are rich in various antithrombotic components, holding significant pharmaceutical value. To investigate the differences in potential antithrombotic capacity among species, this study utilized transcriptome sequencing technology to ...
Rui Ai, Zichao Liu, Zhengguang Zhang, Lizhou Tang, Rujiao Sun, Zuhao Huang, Fang Zhao, Gonghua Lin   +7 more
doaj   +1 more source

WRKY61 Negatively Regulates Aluminum Resistance by Inhibiting the Expression of ALMT1 in Arabidopsis thaliana

Plants
Aluminum (Al) toxicity is a major constraint on crop production in acidic soils. A key mechanism for aluminum resistance in many plants involves the ALMT1-mediated exudation of malate from the root system. This process hinges on the precise regulation of
Aolin Ma, Jie Li, Siqi Liu, Zhixuan Du, Jianjun Zeng, Yonghong Xiao, Guanping Feng   +6 more
doaj   +1 more source

Pathogen Emergence As Complex Biological Invasion: Lessons From Dynamical Systems Modeling

Northeast Journal of Complex Systems, 2023
Infectious disease emergence has become the target of cross-disciplinary efforts that aim to understand and predict the shape of outbreaks. The many challenges involved with the prediction of disease emergence events is a characteristic that infectious ...
Sudam Surasinghe, Marisabel Rodriguez, Victor Meszaros, Jane Molofksy, Salvador Almagro-Moreno, Brandon Ogbunugafor   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source