Results 1 to 10 of about 553,087 (160)

Orthodontic treatment and biological limits: a retrospective clinical trial [PDF]

open access: yesHead & Face Medicine, 2023
Background The fundamental part of every successful orthodontic treatment is the detailed treatment planning including a precise determination of the virtual treatment objective (VTO) while considering the biological and anatomical limits.
Niki Nikoleta Tabancis   +4 more
doaj   +2 more sources

Isobutanol production freed from biological limits using synthetic biochemistry [PDF]

open access: yesNature Communications, 2020
A cell free or synthetic biochemistry approach offers a way to circumvent the many constraints of living cells. Here, the authors demonstrate, via enzyme and process enhancements, the production of isobutanol with the metrics exceeding highly developed ...
Saken Sherkhanov   +9 more
doaj   +2 more sources

Nanocarriers as a Delivery Platform for Anticancer Treatment: Biological Limits and Perspectives in B-Cell Malignancies [PDF]

open access: yesPharmaceutics, 2022
Nanoparticle-based therapies have been proposed in oncology research using various delivery methods to increase selectivity toward tumor tissues. Enhanced drug delivery through nanoparticle-based therapies could improve anti-tumor efficacy and also ...
Sara Bozzer   +4 more
doaj   +2 more sources

The influence of sampling time on indirect reference limits, decision limits, and the estimation of biological variation of random plasma glucose concentrations

open access: yesJournal of Laboratory Medicine, 2021
Plasma glucose concentrations exhibit a pronounced daytime-dependent variation. The oscillations responsible for this are currently not considered in the determination of reference limits (RL) and decision limits.
Özcürümez Mustafa   +5 more
doaj   +2 more sources

Limits on the evolutionary rates of biological traits

open access: yesScientific Reports
This paper focuses on the maximum speed at which biological evolution can occur. I derive inequalities that limit the rate of evolutionary processes driven by natural selection, mutations, or genetic drift.
Luis Pedro García-Pintos
doaj   +4 more sources

Comprehensive Assessment of Druggable Targets in Cortical Neurons Reveals Biological Limits of Cell Type-Specific Neuropharmacology [PDF]

open access: yesBiomedicines
Background: Translational circuit neuroscience delivers many candidate neurons whose manipulation could ameliorate psychiatric symptoms. However, the translation of these cellular targets into molecular targets—proteins selectively expressed in those ...
Leonie Ripp, Dennis Kätzel
doaj   +2 more sources

Correction: Orthodontic treatment and biological limits: a retrospective clinical trial [PDF]

open access: yesHead & Face Medicine
Niki Nikoleta Tabancis   +4 more
doaj   +2 more sources

On the Limitations of Biological Knowledge [PDF]

open access: yesCurrent Genomics, 2012
Scientific knowledge is grounded in a particular epistemology and, owing to the requirements of that epistemology, possesses limitations. Some limitations are intrinsic, in the sense that they depend inherently on the nature of scientific knowledge; others are contingent, depending on the present state of knowledge, including technology.
Dougherty, Edward R, Shmulevich, Ilya
openaire   +2 more sources

Developmental Temperature Affects Life-History Traits and Heat Tolerance in the Aphid Parasitoid Aphidius colemani

open access: yesInsects, 2021
Developmental temperature plays important roles in the expression of insect traits through thermal developmental plasticity. We exposed the aphid parasitoid Aphidius colemani to different temperature regimes (10, 20, or 28 °C) throughout larval ...
Mey Jerbi-Elayed   +4 more
doaj   +1 more source

Fundamental limits of parasitoid-driven host population suppression: Implications for biological control.

open access: yesPLoS ONE, 2023
Parasitoid wasps are increasingly being used to control insect pest populations, where the pest is the host species parasitized by the wasp. Here we use the discrete-time formalism of the Nicholson-Bailey model to investigate a fundamental question-are ...
Abhyudai Singh
doaj   +1 more source

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