Results 1 to 10 of about 548,018 (120)

On the Limitations of Biological Knowledge [PDF]

Current Genomics, 2012
Scientific knowledge is grounded in a particular epistemology and, owing to the requirements of that epistemology, possesses limitations. Some limitations are intrinsic, in the sense that they depend inherently on the nature of scientific knowledge; others are contingent, depending on the present state of knowledge, including technology.
Dougherty, Edward R, Shmulevich, Ilya
openaire   +2 more sources

Informational limits of biological organisms [PDF]

The EMBO Journal, 2018
Genomic analyses have revealed that free‐living biological organisms carry between 10 7 and 10 11 bits of information in their genomes. In large organisms with relatively small population sizes, such as humans, only in the order of 1% of the genomic information is shaped by the environment via natural selection.
openaire   +2 more sources

Revisiting safe biological limits in fisheries

Fish and Fisheries, 2014
AbstractThe appropriateness of three official fisheries management reference points used in the north‐east Atlantic was investigated: (i) the smallest stock size that is still within safe biological limits (SSBpa), (ii) the maximum sustainable rate of exploitation (Fmsy) and (iii) the age at first capture. As for (i), in 45% of the examined stocks, the
Froese R, Coro G, Kleisner K, Demirel N
openaire   +5 more sources

Challenges and Limitations of Biological Network Analysis

BioTech, 2022
High-Throughput technologies are producing an increasing volume of data that needs large amounts of data storage, effective data models and efficient, possibly parallel analysis algorithms. Pathway and interactomics data are represented as graphs and add a new dimension of analysis, allowing, among other features, graph-based comparison of organisms ...
Marianna Milano, Giuseppe Agapito, Mario Cannataro   +2 more
openaire   +3 more sources

Biologically Targeted Magnetic Hyperthermia: Potential and Limitations [PDF]

Frontiers in Pharmacology, 2018
Hyperthermia, the mild elevation of temperature to 40-43°C, can induce cancer cell death and enhance the effects of radiotherapy and chemotherapy. However, achievement of its full potential as a clinically relevant treatment modality has been restricted by its inability to effectively and preferentially heat malignant cells.
David Chang, David Chang, David Chang, May Lim, Jeroen A. C. M. Goos, Jeroen A. C. M. Goos, Ruirui Qiao, Yun Yee Ng, Friederike M. Mansfeld, Friederike M. Mansfeld, Friederike M. Mansfeld, Michael Jackson, Thomas P. Davis, Thomas P. Davis, Maria Kavallaris, Maria Kavallaris   +15 more
openaire   +7 more sources

Limits on the evolutionary rates of biological traits

Scientific Reports
AbstractThis paper focuses on the maximum speed at which biological evolution can occur. I derive inequalities that limit the rate of evolutionary processes driven by natural selection, mutations, or genetic drift. These rate limits link the variability in a population to evolutionary rates.
openaire   +4 more sources

Orthodontic treatment and biological limits: a retrospective clinical trial. [PDF]

Head Face Med, 2023
Tabancis NN, Krey KF, Stahl F, Behnke V, Ratzmann A.   +4 more
europepmc   +1 more source

Nanocarriers as a Delivery Platform for Anticancer Treatment: Biological Limits and Perspectives in B-Cell Malignancies. [PDF]

Pharmaceutics, 2022
Bozzer S, Dal Bo M, Grimaldi MC, Toffoli G, Macor P.   +4 more
europepmc   +1 more source

Biological Monitoring Without Limits [PDF]

Annals of Work Exposures and Health, 2017
John, Cocker, Kate, Jones
openaire   +2 more sources

Isobutanol production freed from biological limits using synthetic biochemistry. [PDF]

Nat Commun, 2020
Sherkhanov S, Korman TP, Chan S, Faham S, Liu H, Sawaya MR, Hsu WT, Vikram E, Cheng T, Bowie JU.   +9 more
europepmc   +1 more source