Results 31 to 40 of about 1,655,931 (299)

Regioselective and stoichiometrically controlled conjugation of photodynamic sensitizers to a HER2 targeting antibody fragment [PDF]

open access: yes, 2014
The rapidly increasing interest in the synthesis of antibody–drug conjugates as powerful targeted anticancer agents demonstrates the growing appreciation of the power of antibodies and antibody fragments as highly selective targeting moieties.
Boyle, Ross W.   +6 more
core   +1 more source

Surface Modification of Fluorescent Nanodiamonds for Biological Applications [PDF]

open access: yesNanomaterials, 2021
Fluorescent nanodiamonds (FNDs) are a new class of carbon nanomaterials that offer great promise for biological applications such as cell labeling, imaging, and sensing due to their exceptional optical properties and biocompatibility. Implementation of these applications requires reliable and precise surface functionalization.
Hak-Sung Jung, Keir C. Neuman
openaire   +3 more sources

Non-mammalian model organisms in epigenetic research : an overview [PDF]

open access: yes, 2020
Recent advances in sequencing technology and genome editing tools had an indisputably enormous impact on our understanding of complex biological pathways and their genetic and epigenetic regulation.
Baruah, Sri Kartik   +3 more
core   +2 more sources

Fast and scalable production of crosslinked polyimide aerogel fibers for ultrathin thermoregulating clothes

open access: yesNature Communications, 2023
Polyimide aerogel fibers hold promise for intelligent thermal management fabrics, but their scalable production faces challenges due to the sluggish gelation kinetics and the weak backbone strength.
Tiantian Xue   +8 more
doaj   +1 more source

Microfluidic synthesis of fibronectin-coated polydopamine nanocomplexes for self-supplementing tumor microenvironment regulation and MR imaging-guided chemo-chemodynamic-immune therapy

open access: yesMaterials Today Bio, 2023
Development of nanomedicines to overcome the hindrances of tumor microenvironment (TME) for tumor theranostics with alleviated side effects remains challenging.
Rui Yang   +7 more
doaj   +1 more source

Electrospun polyvinyl alcohol/carbon dioxide modified polyethyleneimine composite nanofiber scaffolds [PDF]

open access: yes, 2014
A novel biocompatible polyvinyl alcohol/carbon dioxide modified polyethyleneimine (PVA/PEI-CO2) composite nanofiber was fabricated by a green and facile protocol, which reduces the cytotoxicity of PEI through the surface modification of the PEI with CO2.
Bremner, David H.   +4 more
core   +3 more sources

5mC-hydroxylase activity is influenced by the PARylation of TET1 enzyme [PDF]

open access: yes, 2015
5-hydroxymethylcytosine is a new epigenetic modification deriving from the oxidation of 5-methylcytosine by the TET hydroxylase enzymes. DNA hydroxymethylation drives DNA demethylation events and is involved in the control of gene expression ...
CAIAFA, Paola   +3 more
core   +2 more sources

Genetic Diversity and Population Structure of Cannabis Based on the Genome-Wide Development of Simple Sequence Repeat Markers

open access: yesFrontiers in Genetics, 2020
Cannabis has been used as a source of nutrition, medicine, and fiber. However, lack of genomic simple sequence repeat (SSR) markers had limited the genetic research on Cannabis species.
Jiangjiang Zhang   +22 more
doaj   +1 more source

Methanol immersion reduces spherical aberration of water dipping lenses at long wavelengths used in multi-photon laser scanning microscopy [PDF]

open access: yes, 2012
Dipping objectives were tested for multi-photon laser scanning microscopy, since their large working distances are advantageous for thick specimens and the absence of a coverslip facilitates examination of living material.
Bestvater   +28 more
core   +1 more source

Gossypol‐Crosslinked Nanoclusters of Ultrasmall Iron Oxide Nanoparticles for Ultrasound‐Enhanced Precision Tumor Theranostics

open access: yesAdvanced Sensor Research, 2023
Development of tumor microenvironment (TME)‐responsive nanomedicines with simple components for precision tumor theranostics still maintains a great challenge.
Rui Yang   +8 more
doaj   +1 more source

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