Results 41 to 50 of about 1,655,931 (299)

TREEOME: A framework for epigenetic and transcriptomic data integration to explore regulatory interactions controlling transcription [PDF]

, 2015
Motivation: Predictive modelling of gene expression is a powerful framework for the in silico exploration of transcriptional regulatory interactions through the integration of high-throughput -omics data.
Budden, David M, Crampin, Edmund J, Hurley, Daniel G   +2 more
core   +2 more sources

Adaptive response and enlargement of dynamic range [PDF]

, 2011
Many membrane channels and receptors exhibit adaptive, or desensitized, response to a strong sustained input stimulus, often supported by protein activity-dependent inactivation.
A. Csik\'asz-Nagy, A. Lupas, B. A. Mello, B. N. Kholodenko, B. Wark, C. H. Hansen, E. N. Pugh Jr., G. L. Hazelbauer, J. E. Keymer, J. J. Tyson, K. Ogata, M. Behar, M. J. Tindall, M. N. Levit, N. Barkai, P. Dunten, P. Francois, R. A. Normann, R. B. Bourret, S. A. Simms, S. Asakura, S. Marom, T. C. Terwilliger, T. M. Yi, T.Friedlander, V. Sourjik, W. Ma, Y. Tu   +27 more
core   +1 more source

Adsorption Performance and Mechanisms of Copper by Soil Glycoprotein-Modified Straw Biochar

Agriculture
Biochar is one of the most promising crop straw utilization pathways. However, its capacity for adsorbing heavy metals is limited, and there is a potential risk of secondary pollution, highlighting the importance of developing efficient and ...
Zhenyu Chen, Zhiyuan Gao, Yiyuan Xue, Xinchi Yao, Haiyan Shao, Qiang Wang   +5 more
doaj   +1 more source

Modulation of Macrophages Using Nanoformulations with Curcumin to Treat Inflammatory Diseases: A Concise Review

Pharmaceutics, 2022
Curcumin (Cur), a traditional Chinese medicine extracted from natural plant rhizomes, has become a candidate drug for the treatment of diseases due to its anti-inflammatory, anticancer, antioxidant, and antibacterial activities.
Huxiao Sun, Mengsi Zhan, Serge Mignani, Dzmitry Shcharbin, Jean-Pierre Majoral, João Rodrigues, Xiangyang Shi, Mingwu Shen   +7 more
doaj   +1 more source

The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski, Michael C. Frühwald, Gudrun Fleischhack, Stephan Tippelt, Pablo Hernáiz‐Driever, Olaf Witt, Astrid Gnekow, Christof Kramm, Matthias Eyrich, Johannes E. A. Wolf, Hermann Müller, Carsten Friedrich, Uwe R. Kordes, Denise Obrecht‐Sturm, Petra Ketteler, Barbara von Zezschwitz, Pascal Johann, Dominik Sturm, Karoline Nemes, Stefan Schönberger, Till Milde, Brigitte Bison, Monika Warmuth‐Metz, Torsten Pietsch, Ulrich Schüller, Arend Koch, David Capper, Martin Hasselblatt, Christian Thomas, Christian Hagel, Stefan M. Pfister, Felix Sahm, David T. W. Jones, Martin U. Schuhmann, Jürgen Krauss, Pedram Emami, Ahmed El Damaty, Rolf D. Kortmann, Rudolf Schwarz, Jürgen Debus, Mechthild Krause, Fabian Pohl, Holger Ottensmeier, Lisa Bußenius, Katja Baust, Andreas Faldum, Cecile Ronckers, Desiree Grabow, Martin Benesch, Thomas Perwein, Karin Dieckmann, Irene Slavc, Johannes Gojo, Nicolas U. Gerber, André O. von Bueren, Katrin Scheinemann, Gabriele Calaminus, Beate Timmermann, Ulrich‐Wilhelm Thomale, Martin Mynarek   +59 more
wiley   +1 more source

Multi-modal imaging for dynamic visualization of osteogenesis and implant degradation in 3D bioprinted scaffolds

Bioactive Materials
In situ monitoring of bone regeneration enables timely diagnosis and intervention by acquiring vital biological parameters. However, an existing gap exists in the availability of effective methodologies for continuous and dynamic monitoring of the bone ...
Qian Feng, Kanwal Fatima, Ai Yang, Chenglin Li, Shuo Chen, Guang Yang, Xiaojun Zhou, Chuanglong He   +7 more
doaj   +1 more source

Physical-chemical Properties and in vitro Biocompatibility Assessment of Spider Silk, Collagen and Polyurethane Nanofiber Scaffolds for Vascular Tissue Engineering

Nano Biomedicine and Engineering, 2009
In this study, three kinds of nanofiber scaffolds including spider silks (SS), collagen, and polyurethane (PU) were fabricated by electrospinning technique.
Chuanglong He, Lei Zhang, Hongsheng Wang, Fan Zhang, Xiumei Mo   +4 more
doaj   +1 more source

Chemical Modification of Polysaccharides: A Review of Synthetic Approaches, Biological Activity and the Structure–Activity Relationship

Molecules, 2023
Natural polysaccharides are macromolecular substances with great potential owing to their wide biological activity and low toxicity. However, not all polysaccharides have significant pharmacodynamic activity; hence, appropriate chemical modification ...
Tianbo Liu, Qianqian Ren, Shuang Wang, Jianing Gao, Congcong Shen, Shengyu Zhang, Yanhong Wang, Feng Guan   +7 more
doaj   +1 more source

Autonomy and the Ethics of Biological Behaviour Modification [PDF]

, 2014
Much disease and disability is the result of lifestyle behaviours. For example, the contribution of imprudence in the form of smoking, poor diet, sedentary lifestyle, and drug and alcohol abuse to ill-health is now well established.
Douglas, Thomas, Persson, Ingmar, Savulescu, Julian   +2 more
core  

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij, Catia Olianti, Herve Brisse, Pier Luigi Di Paolo, Maria Garganese, Tejas Kapadia, Jurgen Schaefer, Hugh Wallace, Simon Wan, Bart de Keizer, Irmina Sefic Pasic, Julian Rogasch   +11 more
wiley   +1 more source