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Advanced Science, EarlyView.THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu +10 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin +12 more
wiley +1 more source
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Structural Basis of Biological Nitrogen Fixation
Chemical Reviews, 1996[no abstract] ; © 1996 American Chemical Society. Received April 26, 1996 (Revised Manuscript Received July 11, 1996) The contributions of our group members who made this review possible are greatly appreciated, as are discussions with our nitrogenase colleagues.
Douglas C Rees
exaly +4 more sources
Annual Review of Nutrition, 1993
Biological nitrogen fixation (BNF) is the process of the reduction of dinitrogen from the air to ammonia carried out by a large number of species of free-living and symbiotic microbes called diazotrophs. BNF presents an inexpensive and environmentally sound, sustainable approach to crop production and constitutes one of the most important Plant Growth ...
R H, Burris, G P, Roberts
openaire +2 more sources
Biological nitrogen fixation (BNF) is the process of the reduction of dinitrogen from the air to ammonia carried out by a large number of species of free-living and symbiotic microbes called diazotrophs. BNF presents an inexpensive and environmentally sound, sustainable approach to crop production and constitutes one of the most important Plant Growth ...
R H, Burris, G P, Roberts
openaire +2 more sources
2022
Discover the positive and helpful contributions made by microorganisms to various areas of human health, food preservation and production, biotechnology, industry, environmental clean up and sustainable agriculture.
de Bruijn, Frans +5 more
openaire +3 more sources
Discover the positive and helpful contributions made by microorganisms to various areas of human health, food preservation and production, biotechnology, industry, environmental clean up and sustainable agriculture.
de Bruijn, Frans +5 more
openaire +3 more sources
2008
Introduction 1 Nitrogen-Fixing Organisms 2 Nitrogenase and Nitrogen Fixation 2 Ammonia Assimilation 4 Diazothrophic Bacteria – Plant Symbioses 4 Rhizobia–Legume Symbiosis 4 Frankia-Dicotyledon Symbiosis 6 Endophytic Diazotrophic Bacteria–Cereal Association 9 Nitrogen Fixation in Free-Living Cyanobacteria 9 Diazotrophic Cyanobacteria–Plant Symbioses 10 ...
RASCIO, NICOLETTA, LA ROCCA, NICOLETTA
openaire +2 more sources
Introduction 1 Nitrogen-Fixing Organisms 2 Nitrogenase and Nitrogen Fixation 2 Ammonia Assimilation 4 Diazothrophic Bacteria – Plant Symbioses 4 Rhizobia–Legume Symbiosis 4 Frankia-Dicotyledon Symbiosis 6 Endophytic Diazotrophic Bacteria–Cereal Association 9 Nitrogen Fixation in Free-Living Cyanobacteria 9 Diazotrophic Cyanobacteria–Plant Symbioses 10 ...
RASCIO, NICOLETTA, LA ROCCA, NICOLETTA
openaire +2 more sources
Nitrogenase and biological nitrogen fixation
Biochemistry, 1994Biological nitrogen fixation is catalyzed by the nitrogenase enzyme system which consists of two metalloproteins, the iron (Fe-) protein and the molybdenum-iron (MoFe-) protein. Together, these proteins mediate the ATP-dependent reduction of dinitrogen to ammonia.
Kim, Jongsun, Rees, Douglas C.
openaire +3 more sources
2005
Nitrogen (N2) fixation is the basis of the global N cycle. Therefore, it is not surprising that the ability to fix atmospheric N2 evolved in the “primeval soup” and is deeply rooted in the evolutionary tree of life. Despite this, nitrogenase remains an enzyme exclusive to prokaryotes; no eukaryote has been described that can fix N2 except through a ...
Giller, K.E., Mapfumo, P.
+6 more sources
Nitrogen (N2) fixation is the basis of the global N cycle. Therefore, it is not surprising that the ability to fix atmospheric N2 evolved in the “primeval soup” and is deeply rooted in the evolutionary tree of life. Despite this, nitrogenase remains an enzyme exclusive to prokaryotes; no eukaryote has been described that can fix N2 except through a ...
Giller, K.E., Mapfumo, P.
+6 more sources
2015
Biological nitrogen fixation is a process by which nitrogen in the atmosphere is converted into ammonia. Legumes also include major food and feed crop species, such as soybean, pea, clover, chickpea, alfalfa, and mungbean, representing the second largest group of food and feed crops grown globally.
de Bruijn, Frans Johannes +1 more
+5 more sources
Biological nitrogen fixation is a process by which nitrogen in the atmosphere is converted into ammonia. Legumes also include major food and feed crop species, such as soybean, pea, clover, chickpea, alfalfa, and mungbean, representing the second largest group of food and feed crops grown globally.
de Bruijn, Frans Johannes +1 more
+5 more sources