Results 41 to 50 of about 99,413 (299)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Molybdenum supply and biological fixation of nitrogen by two Brazilian common bean cultivars

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental
The common bean has been considered to have low biological nitrogen fixation capacity; however, this process can be made more effective with molybdenum (Mo) supplementation.
Alinne da Silva   +3 more
doaj   +1 more source

Extracellular electron transfer drives ATP synthesis for nitrogen fixation by Pseudomonas stutzeri

open access: yesElectrochemistry Communications, 2023
Biological nitrogen fixation is a key step in the reduction of N2 to available nitrogen in the global nitrogen cycle. Pseudomonas stutzeri A1501 is an electroactive diazotroph and previous studies have shown that its nitrogen fixation performance is ...
Shanshan Chen   +5 more
doaj   +1 more source

Abundances of Iron-Binding Photosynthetic and Nitrogen-Fixing Proteins of Trichodesmium Both in Culture and In Situ from the North Atlantic

open access: yes, 2012
Marine cyanobacteria of the genus Trichodesmium occur throughout the oligotrophic tropical and subtropical oceans, where they can dominate the diazotrophic community in regions with high inputs of the trace metal iron (Fe).
Pratt, Nicola J.   +17 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Symbioses between cyanobacterial communities and feather mosses in boreal forests and consequences for dinitrogen fixation [PDF]

open access: yes, 2013
Feather moss-cyanobacteria associations, although still poorly understood, are recognised as essential for the regulation of nitrogen (N) input into N-limited ecosystems such as boreal forests due to their ability to carry out N2-fixation.
Bay, Guillaume
core  

The genetics of symbiotic nitrogen fixation: Comparative genomics of 14 rhizobia strains by resolution of protein clusters

open access: yes, 2012
The symbiotic relationship between legumes and nitrogen fixing bacteria is critical for agriculture, as it may have profound impacts on lowering costs for farmers, on land sustainability, on soil quality, and on mitigation of greenhouse gas emissions ...
John Howieson   +14 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Nitrogen Isotopes in the Global Ocean [PDF]

open access: yes, 2013
Nitrogen is an essential nutrient for life. Its low abundance throughout much of the sunlit surface ocean limits the growth of primary producers that form the base of ocean ecosystems.
Somes, Christopher J.   +1 more
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

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