Results 191 to 200 of about 55,716 (260)

Norroa™ as a dsRNA biopesticide for <i>Varroa destructor</i>: insights from New Zealand research on mode of action, field efficacy, non-target effects, and social acceptance. [PDF]

open access: yesFront Insect Sci
Lester PJ   +9 more
europepmc   +1 more source

Mapping Causal Biology: Mendelian Randomization in the Era of Big Data

open access: yesMed Research, EarlyView.
Mendelian randomization (MR) leverages genetic variants to mitigate confounding biases in causal inference. This review systematically maps MR's methodological evolution, highlights its expanding applications in epidemiology and drug target validation, and outlines future directions for overcoming current biases through dynamic, multi‐omics, and cross ...
Xuanlu Shen   +10 more
wiley   +1 more source

The toxin–antitoxin complex Fic‐1–AntF functions as a deAMPylase that regulates the activity of DNA gyrase

open access: yesmLife, EarlyView.
Abstract Toxin–antitoxin (TA) systems found in diverse bacteria play important roles in their adaptation to changing environments. The toxin of the Fic‐1–AntF TA pair from Pseudomonas bijieensis strain 2P24 inhibits bacterial DNA replication by attacking the subunit B of DNA gyrase (GyrB) via AMPylation, while the antitoxin AntF blocks its enzymatic ...
Furong Chen   +6 more
wiley   +1 more source

T(w)o Patch or Not T(w)o Patch: A Novel Biocontrol Model

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT A number of top‐down biocontrol models have been proposed where the introduced predators' efficacy is enhanced via the provision of additional food (AF). However, if the predator has a pest‐dependent monotone functional response, pest extinction is unattainable. In the current manuscript, we propose a model where a predator with pest‐dependent
Urvashi Verma   +2 more
wiley   +1 more source

A Geometrically Regularized Gradient‐Damage Model With Orthogonality‐Based Energy Split for Dynamic Anisotropic Compression‐Shear Fracture

open access: yesInternational Journal for Numerical and Analytical Methods in Geomechanics, EarlyView.
ABSTRACT This study proposes a novel geometrically regularized gradient‐damage model for simulating dynamic mixed‐mode fracture in orthotropic materials with tension–compression asymmetry. In this model, a thermodynamic framework is formulated by incorporating damage dissipation into internal energy evolution, from which the constitutive relation and ...
Hui Li, Shanyong Wang
wiley   +1 more source

Interplanetary frontiers: terraforming from an invasion science perspective

open access: yesOikos, EarlyView.
The pursuit of a multi‐planetary existence represents one of humanity's greatest frontiers. If applied justly, it offers an opportunity to extend its civilization's lifespan amid escalating sustainability crises on Earth. One approach increasingly gaining traction is terraforming, a hitherto theoretical ecological and evolutionary experiment revolving ...
Teun Everts   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy