Results 81 to 90 of about 5,013,780 (327)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Accommodating Probability to Durability as Facing the Onset of Biological Phenomena from Within
Philosophies, 2020 Life distinguishes itself from non-life in taking advantage of the cohesion of temporal origin which non-life cannot afford. The temporal cohesion letting the local participants adhere to each other in a contemporaneous manner refers to an instance of ...
Koichiro Matsuno
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Exploratory research on bioactive natural products with a focus on biological phenomena
Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2010 The discovery of new basic compounds holds the key for advancing material sciences. We have focused on the identification and characterization of natural key compounds that control biologically and physiologically intriguing phenomena.
D. Uemura
semanticscholar +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Supramolecular assembly of protein building blocks: from folding to function
Nano Convergence, 2022 Several phenomena occurring throughout the life of living things start and end with proteins. Various proteins form one complex structure to control detailed reactions.
Nam Hyeong Kim +6 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Thermodynamic Analysis of Interactions in Langmuir Monolayers Imitating Bacterial Membranes
ProceedingsBacteria belonging to the Legionella gormanii species cause respiratory diseases [...]
Katarzyna Pastuszak +2 more
doaj +1 more source
Presentation and representation of biological phenomena from a vegetable garden [PDF]
Investigações em Ensino de Ciências, 2007 This paper proposes a methodology for science education based on the triad perceive/associate/experience. The analysis performed relied upon Charles Sanders Peirce’s semiotics framework.
Ana Maria de Andrade Caldeira +1 more
doaj
From bottom-up approaches to levels of organization and extended critical transitions
Frontiers in Physiology, 2012 Biological thinking is structured by the notion of level of organization. We will show that this notion acquires a precise meaning in critical phenomena: they disrupt, by the appearance of infinite quantities, the mathematical (possibly equational ...
Giuseppe eLongo +6 more
doaj +1 more source