Results 61 to 70 of about 257,733 (262)
Presentation and representation of biological phenomena from a vegetable garden [PDF]
Investigações em Ensino de Ciências, 2007 This paper proposes a methodology for science education based on the triad perceive/associate/experience. The analysis performed relied upon Charles Sanders Peirce’s semiotics framework.
Ana Maria de Andrade Caldeira +1 more
doaj
Evolutionary Applications, 2020 Introduction Brown planthoppers (Nilaparvata lugens) are the most serious insect pests of rice, one of the world's most important staple crops. They reproduce year‐round in the tropical parts of their distribution, but cannot overwinter in the temperate ...
James P. Hereward +5 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Nonlinear phenomena of Fröhlich phonons in biological media
Moldavian Journal of the Physical Sciences, 2013 Nonlinear cooperative stationary phenomena are studied for the interaction of Bose-condensed phonons with millimeter electromagnetic radiation in the biological media.
Rotaru, Anatol +2 more
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HeritageArchival materials are increasingly vulnerable to damage from chemical, physical, biological, and environmental factors, including climate change-related extreme weather events such as torrential rains and flash floods.
Tullia Carla David +5 more
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Hematopoietic Stem Cell and Fibroblast Proliferation Following Platelet Electrostimulation
IEEE Access, 2018 The increasing use of activated platelet rich plasma (PRP), or platelet gel, for wound healing has highlighted the disadvantages of using bovine thrombin (BT), an animal derived platelet activator, including high cost and antibody stimulation.
Jason Castle +7 more
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source