Results 51 to 60 of about 3,543,672 (267)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Thermodynamic Analysis of Interactions in Langmuir Monolayers Imitating Bacterial Membranes

Proceedings
Bacteria belonging to the Legionella gormanii species cause respiratory diseases [...]
Katarzyna Pastuszak, Małgorzata Jurak, Marta Palusińska-Szysz   +2 more
doaj   +1 more source

Presentation and representation of biological phenomena from a vegetable garden [PDF]

Investigações em Ensino de Ciências, 2007
This paper proposes a methodology for science education based on the triad perceive/associate/experience. The analysis performed relied upon Charles Sanders Peirce’s semiotics framework.
Ana Maria de Andrade Caldeira, Selma Rosana Santiago Manechine   +1 more
doaj  

Migration dynamics of an important rice pest: The brown planthopper (Nilaparvata lugens) across Asia—Insights from population genomics

Evolutionary Applications, 2020
Introduction Brown planthoppers (Nilaparvata lugens) are the most serious insect pests of rice, one of the world's most important staple crops. They reproduce year‐round in the tropical parts of their distribution, but cannot overwinter in the temperate ...
James P. Hereward, Xuhong Cai, Ambrocio Melvin A. Matias, Gimme H. Walter, Chenxi Xu, Yongmo Wang   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1895

, 1896
Annual report of the Marine Biological Laboratory in Woods Hole. 1895.
Marine Biological Laboratory (Woods Hole MA)
core  

Nonlinear phenomena of Fröhlich phonons in biological media

Moldavian Journal of the Physical Sciences, 2013
Nonlinear cooperative stationary phenomena are studied for the interaction of Bose-condensed phonons with millimeter electromagnetic radiation in the biological media.
Rotaru, Anatol, Ciobanu, Nellu, Tronciu, Vasile   +2 more
doaj  

Effects of Saline Solutions on Paper-Based Cultural Heritage: Non-Invasive Techniques for Studying Flooded Ancient Books

Heritage
Archival materials are increasingly vulnerable to damage from chemical, physical, biological, and environmental factors, including climate change-related extreme weather events such as torrential rains and flash floods.
Tullia Carla David, Francesca Assunta Pisu, Stefania Porcu, Carlo Maria Carbonaro, Jarmila Kodric, Daniele Chiriu   +5 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source