Raport privind rezultatele testului de competentă a laboratoarelor pentru determinarea nivelului de microorganisme din produsele farmaceutice [PDF]
Medicamentul Veterinar, 2014 The present study describes the results obtained by the Microbiological Control Laboratory from Institute for Control of Biological Products and Veterinary Medicines after participating in the proficiency testing scheme study on low – level microbial ...
Simona Sturzu +4 more
doaj
A Review of the Establishment of the Seed Lot System in the Production of Biological Products and Its Importance. [PDF]
Arch Razi Inst, 2022 Soleimani S.
europepmc +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
VaccinesMadin–Darby canine kidney (MDCK) cells are commonly used to produce cell-based influenza vaccines. However, the role of the low-serum medium on the proliferation of MDCK cells and the propagation of the influenza virus has not been well studied.
Ming Cai +13 more
doaj +1 more source
Raport privind controlul calită܊ii microbiologice a produselor farmaceutice veterinare în anul 2013 [PDF]
Medicamentul Veterinar, 2014 The microbiological contamination of pharmaceutical products could have major consequences on the physical – chemical characteristics, safety and efficiency of the medicinal products and also on the out of specification products recall-associated costs ...
Simona Sturzu +4 more
doaj
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Antibiotic Resistance to Mycobacterium tuberculosis and Potential Use of Natural and Biological Products as Alternative Anti-Mycobacterial Agents. [PDF]
Antibiotics (Basel), 2022 Arrigoni R +5 more
europepmc +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Uptake and Competition Among Biosimilar Biological Products in the US Medicare Fee-for-Service Population. [PDF]
J Gen Intern Med, 2022 Kozlowski S +6 more
europepmc +1 more source