Results 171 to 180 of about 1,399,233 (310)

Availability and reimbursement of biological products for severe asthma in Bulgaria. [PDF]

SAGE Open Med, 2020
Milushewa P, Doneva M, Petrova G.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Establishment of Nucleic Acid Amplification Technology for the Detection of <i>Mycoplasma</i> in Biological Products. [PDF]

Molecules
Guo Y, Qin X, Zhang J, Bi H, Hou S, Ding Y, Pei D, Li X, Pan Y, Sun X, Liang C.   +10 more
europepmc   +1 more source

Comparability Considerations and Challenges for Expedited Development Programs for Biological Products. [PDF]

Drugs R D, 2020
Schrieber SJ, Putnam WS, Chow ECY, Cieslak J, Zhuang Y, Martin SW, Hanson P, Maggio F, Rosado LAR.   +8 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Using Biotechnology to Lower Production Costs of Biofuels in Canada: Will it Hinder the Growth of an Export Industry?

Bio-based fuels represent one of the most viable alternatives to petroleum-based fuel to meet transportation needs in the 21st century. The biofuel industry is in its infancy in Canada but shows considerable growth opportunity. The international interest
Loppacher, Laura J.
core  

Processes and products for enhanced biological product

, 2015
The invention relates to genetic constructs encoding a compartmenting peptide, wherein expression of the compartmenting peptide leads to formation of a droplet body comprising a targeted biological product, and to vectors including such constructs.
Yuan, Shuhua, Wang, Xin
core  

Microorganism-Based Biological Products for Agriculture: From Strain Selection to Production Organization. [PDF]

Microorganisms
Sadanov AK, Baimakhanova G, Baimakhanova BB, Orazymbet S, Ratnikova IA, Smirnova I, Aitkaliyeva GS, Belkozhayev AM, Kossalbayev BD.   +8 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Advancements in the application of reporter gene cell lines in bioactivity evaluation of biological products. [PDF]

Bioresour Bioprocess
Yi K, Wang C, Lu H.
europepmc   +1 more source