Results 221 to 230 of about 2,696,596 (307)

Metabolic products of microorganisms. 234 Urdamycins, new angucycline antibiotics from Streptomyces fradiae. I Isolation, characterization and biological properties.

, 1986
Hannelore Drautz, Hans Zähner, Jürgen Rohr, Axel Zeeck   +3 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Report of the AAPS Guidance Forum on the FDA Draft Guidance for Industry: "Drug Products, Including Biological Products, that Contain Nanomaterials". [PDF]

AAPS J, 2019
de Vlieger JSB, Crommelin DJA, Tyner K, Drummond DC, Jiang W, McNeil SE, Neervannan S, Crist RM, Shah VP.   +8 more
europepmc   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Removal of the innocuity test from The International Pharmacopoeia and WHO recommendations for vaccines and biological products.

Biologicals, 2020
Lei D, Schmidt H, Knezevic I, Zhou T, Kang HN, Kopp S.   +5 more
europepmc   +1 more source

Comment on "Analysis of Pharmacokinetic and Pharmacodynamic Parameters in EU-Versus US-Licensed Reference Biological Products: Are In Vivo Bridging Studies Justified for Biosimilar Development?" [PDF]

BioDrugs, 2019
Webster CJ, Woollett GR.
europepmc   +1 more source

Partial purification and biological activity of the product of chemically synthesized human growth hormone gene expression in Escherichia coli.

, 1985
Tadashi Oshizawa, Tadao Terao, Hiroshi Sato, Toshio Kimura, Hideo Fukuda, Tsuyoshi Tanimoto, Shingo Niimi, Jiro Kawamura, Takao Hayakawa, E. Otsuka, Morio Ikehara   +10 more
openalex   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Biological effects of inhaled TiCl/sub 4//NH/sub 4/OH reaction products in Sprague-Dawley rats and Syrian hamsters

, 1980
David M. Smith, C Pigg, R.F. Archuleta
openalex   +2 more sources

Biological Complementary Therapies: A Focus on Botanical Products in Diabetes [PDF]

, 2001
Laura Shane‐McWhorter
openalex   +1 more source