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Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu+9 more
wiley +1 more source
Biology-inspired engineering for circular bioeconomy systems. [PDF]
Verma BP, Jones JW.
europepmc +1 more source
Liver‐specific lncRNAs associated with liver cancers
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina+3 more
wiley +1 more source
Development of molecular diagnostic methods to distinguish acerola species for quality assurance of food, dietary supplements and natural health products. [PDF]
Ragupathy S+4 more
europepmc +1 more source
Multiomics profiling reveals systemic biological responses to severe subacute exposure to heated tobacco products in rats. [PDF]
Zhou P+7 more
europepmc +1 more source
Editorial for Special Issue "Molecular Insights into Food-Derived Natural Products and Their Biological Activities". [PDF]
Li Y.
europepmc +1 more source
Bibliometric Analysis of Papaya and Dragon Fruit By-Products. [PDF]
Barroso-Torres N, Lobo MG, Dorta E.
europepmc +1 more source
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Digital-to-biological converter for on-demand production of biologics
Nature Biotechnology, 2017Manufacturing processes for biological molecules in the research laboratory have failed to keep pace with the rapid advances in automization and parellelization. We report the development of a digital-to-biological converter for fully automated, versatile and demand-based production of functional biologics starting from DNA sequence information ...
Daniel G. Gibson+8 more
openaire +3 more sources