Results 281 to 290 of about 2,696,596 (307)

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Legal questions of AI-generated immunological products for infectious diseases. [PDF]

Hum Vaccin Immunother
Zumárraga J, McConnell MJ, López D, Martín-Galiano AJ.   +3 more
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

In-depth comparison of commercial <i>Trichoderma-</i>based products: integrative approaches to quantitative analysis, taxonomy and efficacy. [PDF]

Front Microbiol
Kulik T, Staniszewska P, Wiśniewski P, Treder Z, Przybylski M, Wrońska E, Maździarz M, Krawczyk K, Bilska K, Paukszto Ł, Olszewski J.   +10 more
europepmc   +1 more source

Whey: Composition, Processing, Application, and Prospects in Functional and Nutritional Beverages-A Review. [PDF]

Foods
Mirzakulova A, Sarsembaeva T, Suleimenova Z, Kowalski Ł, Gajdzik B, Wolniak R, Bembenek M.   +6 more
europepmc   +1 more source

The application of desymmetric enantioselective reduction of cyclic 1,3-dicarbonyl compounds in the total synthesis of terpenoid and alkaloid natural products. [PDF]

Beilstein J Org Chem
Tan DX, Han FS.
europepmc   +1 more source

Exploring Regulatory Frameworks for Exosome Therapy: Insights and Perspectives. [PDF]

Health Care Sci
Li Q, Li Y, Shao J, Sun J, Hu L, Yun X, Liuqing C, Gong L, Wu S.   +8 more
europepmc   +1 more source

Advancements in nasal drug delivery system of natural products. [PDF]

Front Pharmacol
Hsu Y, Yang J, Cao M, Xu T, He J, Hong H, Jiang L, Peng S, Xiong P.   +8 more
europepmc   +1 more source

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Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Lorenzo Cohen, Karen M Mustian, Ricardo Ghelman   +2 more
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