Results 211 to 220 of about 3,239,321 (318)

Quality of Life in Autistic Children: Discrepancies Between Self‐ and Caregiver‐Proxy Reports and Associations With Individual Characteristics

open access: yesAutism Research, EarlyView.
ABSTRACT Quality of life (QoL) is important for everyone and has been identified as a priority for autistic people. However, studies typically focus on caregiver‐proxy‐reported QoL and its related individual characteristics, even though self‐ and caregiver‐proxy‐reported QoL may differ in autistic children. In 74 autistic children (5.04–10.99 years old,
Emily C. Skaletski   +6 more
wiley   +1 more source

A Frank Assessment of SHANK: Impacts of Pathogenic Variations in SHANK3 on Preclinical Models of Phelan McDermid Syndrome

open access: yesAutism Research, EarlyView.
ABSTRACT Although there are as many as 40 preclinical models of the neurodevelopmental disorder Phelan McDermid syndrome (PMS, or 22q13.3 deletion syndrome), detailed phenotypic analyses to compare the effects of different pathogenic variants and inform treatment design are lacking.
Vic Lin   +7 more
wiley   +1 more source

Screen to Screen Versus Face to Face: Evaluating Telehealth Autism Diagnostic Assessments for Young Children in a Diverse Clinical Setting

open access: yesAutism Research, EarlyView.
ABSTRACT Access to autism diagnostic assessments continues to be problematic for many families and children. While telehealth assessments have been shown to be feasible and reliable in research settings, less is known about the agreement between telehealth autism assessments compared with in‐person evaluations in clinical settings with linguistic ...
Rebecca Sutherland   +11 more
wiley   +1 more source

Biological psychiatry: time for new paradigms

open access: yesBritish Journal of Psychiatry, 2013
D. Linden
semanticscholar   +1 more source

Development of Respiratory Sinus Arrhythmia in Young Infants With Autism Spectrum Disorder, Preterm Birth, and Typical Development

open access: yesAutism Research, EarlyView.
ABSTRACT Respiratory sinus arrhythmia (RSA) is a key index of parasympathetic function and environmental adaptability. Lower resting RSA has been linked to preterm (PT) birth in infancy and autism spectrum disorder (ASD) in childhood, yet RSA across the first 2 years in young infants born PT or later diagnosed with ASD remains unknown.
Jessica Bradshaw   +3 more
wiley   +1 more source

Differences in the Social Experiences of Autistic and Non‐Autistic Adolescents by Gender

open access: yesAutism Research, EarlyView.
ABSTRACT Adolescence is a time of complex social and emotional development when friendships become of particular importance. Previous research has highlighted differences in the social experience of autistic and non‐autistic adolescents, as well as that of autistic girls and boys.
Ellie Roberts   +2 more
wiley   +1 more source

Altered Primary Somatosensory Neuron Development in a Pten Heterozygous Model for Autism Spectrum Disorder

open access: yesAutism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by deficits in social interactions, repetitive behaviors, and hyper‐ or hyposensitivity to sensory stimuli. The cellular mechanisms underlying the emergence of abnormal sensory sensitivity in ASD are not fully understood.
Alejandra Fernandez   +3 more
wiley   +1 more source

Population pharmacokinetic modelling of prednisolone in systemic lupus erythematosus patients: Analysis of exposure and disease activity

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Prednisone is a widely used glucocorticoid in the treatment of lupus, although its dosing is often determined empirically. Prednisolone, the active metabolite of prednisone, is found in its free form in the serum. The goal of this study was to develop a population pharmacokinetic model in patients with systemic lupus erythematosus (SLE ...
Naïm Bouazza   +26 more
wiley   +1 more source

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