Results 101 to 110 of about 62,914 (286)

Uncovering Patterns and Trends in Big Data-Driven Research Through Text Mining of NSF Award Synopses

open access: yesAnalytics
The rapid expansion of big data has transformed research practices across disciplines, yet disparities exist in its adoption among U.S. institutions of higher education.
Arielle King, Sayed A. Mostafa
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Type Disciplines for Analysing Biologically Relevant Properties

open access: yes, 2009
The calculus of looping sequences is a formalism for describing evolution of biological systems by means of term rewriting rules. We propose to enrich this calculus with type disciplines to guarantee the soundness of reduction rules with respect to ...
Dezani-Ciancaglini, Mariangiola   +4 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Widening participation in polar sciences from a grassroots level: Evaluating two UK polar outreach events

open access: yesJournal of Glaciology
The polar regions are crucial parts of the global climate system and yet are highly vulnerable to anthropogenic stresses and climate change. Polar scientists study a wide range of disciplines across the physical, biological and sociological systems to ...
Roseanna J. Mayfield   +7 more
doaj   +1 more source

Charles Darwin goes to school: the role of cartoons and narrative in setting science in an historical context

open access: yes, 2009
Science education is under revision. Recent changes in society require changes in education to respond to new demands. Scientific literacy can be considered a new goal of science education and the epistemological gap between natural sciences and literacy
SILVA, Paulo Roberto Costa da   +5 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The nature of science in teacher education: reflections from a course of teacher preparation in Biological Sciences [PDF]

open access: yesInvestigações em Ensino de Ciências, 2012
This paper is a theoretical review of studies on the Nature of Science in the teacher formation in Science Education area. We have had as a starting point the landscape of metascience.
Argus Vasconcelos de Almeida   +1 more
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Research Status of Caenorhabditis elegans Model in Toxicology and Its Applications in Forensic Science

open access: yesFayixue Zazhi
Caenorhabditis elegans, as an emerging model organism, has been widely used in multiple disciplines such as medicine, life science, and environmental science in recent years, due to its characteristics of short life cycle, clear genetic background ...
LI Zhuo   +4 more
doaj   +1 more source

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