Results 121 to 130 of about 62,914 (286)
Disciplining anthropological demography [PDF]
This study furthers the epistemological development of anthropological demography, and its role in understanding the demography of Europe. Firstly we situate anthropological demography against the context of an evolving world of research in which ...
Ernestina Coast +2 more
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Biological information specialists for biological informatics
, 2007 Data management and integration are complicated and ongoing problems that will require commitment of resources and expertise from the various biological science communities.
P Bryan Heidorn +5 more
core +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
, 2020 Objetivo: analisar a importância atribuída pelos estudantes às disciplinas das Ciências Biológicas e da Saúde em um Curso de Graduação em Enfermagem. Método: Trata-se de um estudo descritivo com uma abordagem quantitativa na modalidade não probabilística por conveniência realizado com 221 estudantes do curso de enfermagem de uma universidade pública ...
Pereira, Fabrício da Gama +3 more
openaire +1 more source
Network of Cooperation Between Science Organizations
, 2015 Appreciation of the fact that our planet functions as a system, i.e., the Earth System (ES), defined as “the interacting physical, chemical and biological global-scale cycles (often called biogeochemical cycles) and energy fluxes which provide the ...
Steffen, Will +3 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 2004 330-335About 170 EMR schemes are selected every year in 6 major areas of science including engineering. Five years data show that there is a wide variation in number and percentage of schemes recommended in different disciplines.
Rani, Kanta +2 more
core