Results 41 to 50 of about 309,058 (173)
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
The Relevance of Evolutionary Science For Economic Theory and Policy [PDF]
NSF’s “Dear Colleague Letter” reflects the widely perceived need to go beyond current economic theory in the formulation of public policy. At the same time, there is a profound lack of unity among the disciplines that comprise the behavioral, social, and
David Sloan Wilson, John M. Gowdy
core
, 2006 Ever since the word ‘ROBOT’ first appeared in a science\ud fiction in 1921, scientists and engineers have been trying\ud different ways to create it. Present technologies in\ud mechanical and electrical engineering makes it possible\ud to have robots in ...
Wang, Mr. L.
core
Bridging Physics and Biology Teaching through Modeling [PDF]
, 2013 As the frontiers of biology become increasingly interdisciplinary, the physics education community has engaged in ongoing efforts to make physics classes more relevant to life sciences majors.
Anne-Marie Hoskinson +23 more
core +3 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Preliminary analysis of a radiobiological experiment for LifeSat [PDF]
With the possibility of performing radiation life science experiments on a dedicated satellite (LifeSat) in space, a combined effort in radiation physics and radiation dosimetry, in addition to radiation biology, is clearly required to ensure that ...
Atwell, William +5 more
core +1 more source
The molecular imaging suite: applications in nanotechnology, targeted imaging and cell tracking [PDF]
, 2012 The blurring of the boundaries between the disciplines of engineering and the biological sciences has revolutionized medicine. Medicine is still a science of decisionmaking under uncertainty.
Ruggiero, A. (Alessandro)
core +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
Use of shuttle for life sciences [PDF]
The use of the space shuttle in carrying out biological and medical research programs, with emphasis on the sortie module, is examined. Detailed descriptions are given of the goals of space life science disciplines, how the sortie can meet these goals ...
Mcgaughy, R. E.
core +1 more source