Results 41 to 50 of about 83,797 (278)

Frozen section histopathology and preanalytical factors affecting nucleic acid integrity in biobanked fresh-frozen human cancer tissues [PDF]

open access: yesJournal of Pathology and Translational Medicine
Background In this study, we evaluated the effects of storage duration and ischemic time on nucleic acid quality of fresh-frozen tissue (FFT) from colon adenocarcinoma (COAD), hepatocellular carcinoma (HCC), and renal cell carcinoma (RCC) collected at ...
Soungeun Kim   +4 more
doaj   +1 more source

Women Epidemiology Lung Cancer (WELCA) study: reproductive, hormonal, occupational risk factors and biobank

open access: yesBMC Public Health, 2017
Background Lung cancer aetiology and clinical aspects have been mainly studied in men, although specific risk factors probably exist in women. Here we present the rationale, design and organization of the WELCA study (Women Epidemiology Lung CAncer) that
Isabelle Stücker   +11 more
doaj   +1 more source

An annotated and illustrated identification guide to common mesophotic reef sponges (Porifera, Demospongiae, Hexactinellida, and Homoscleromorpha) inhabiting Flower Garden Banks national marine sanctuary and vicinities

open access: yes, 2022
Sponges are recognized as a diverse and abundant component of mesophotic and deep-sea ecosystems worldwide. In Flower Garden Banks National Marine Sanctuary region within the northwestern Gulf of Mexico, sponges thrive among diverse biological and ...
Hickerson,Emma   +7 more
core   +1 more source

Innovative Research on an AI-Integrated Full-Cycle Intelligent Management System for Donor Semen Specimens in Human Sperm Banks

open access: yesJournal of Information Systems Engineering & Management
With the rapid advancement of assisted reproductive technologies (ART), human sperm banks urgently require a transition from traditional management models to intelligent, data-driven systems. This study proposes a full-cycle status management system that
Ling Wan
semanticscholar   +1 more source

Biobanking in microbiology: From sample collection to epidemiology, diagnosis and research

open access: yesFEMS Microbiology Reviews, 2005
Millions of biological samples, including cells of human, animal or bacterial origin, viruses, serum/plasma or DNA/RNA, are stored every year throughout the world for diagnostics and research.
P. De Paoli
semanticscholar   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Barriers and opportunities in biobank utilization: insights from a 3-year repeated cross-sectional survey of the Female Breast and Genital Disease with Microbiome Biobank Network (FDMNet) in South Korea [PDF]

open access: yesJournal of Yeungnam Medical Science
Background This study aimed to document the patterns, challenges, and opportunities for biobank utilization within the Female Breast and Genital Disease with Microbiome Biobank Network (FDMNet) in South Korea.
Sangzin Ahn   +7 more
doaj   +1 more source

Green plants in the red : a baseline global assessment for the IUCN Sampled Red List Index for Plants

open access: yes, 2015
Plants provide fundamental support systems for life on Earth and are the basis for all terrestrial ecosystems; a decline in plant diversity will be detrimental to all other groups of organisms including humans. Decline in plant diversity has been hard to
Vanessa Coldwell   +171 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Construction and Application of a Biological Sample Library Information Management System Based on a Data Governance System in China [PDF]

open access: yesHealthcare Informatics Research
Objectives This study aimed to develop and implement a hospital-based Biobank Information Management System (Version 1.0) within a structured data governance framework, and to evaluate its effectiveness in improving standardized biospecimen management ...
Ke Wang   +6 more
doaj   +1 more source

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