Results 71 to 80 of about 44,994 (269)
Efficacy and Mechanism EvaluationBackground Almost all large-scale trials of disease-modifying therapeutic agents in critical care have failed to show benefit for patients, which may be explained in part by the clinical and biological heterogeneity inherent in virtually all critical ...
Kiran Reddy +74 more
doaj +1 more source
The beetle fauna of Dominica, Lesser Antilles (Insecta: Coleoptera) : diversity and distribution [PDF]
, 2006 The beetle fauna of the island of Dominica is summarized. It is presently known to contain 269 genera, and 361 species (in 42 families), of which 347 are named at a species level. Of these, 62 species are endemic to the island.
Peck, Stewart B.
core +1 more source
Advanced Science, EarlyView.We developed a macrophage‐based therapeutic platform, termed trackable tolerogenic macrophages (TTM), for dual‐function immunomodulation and visualization in vivo. TTM cells were engineered to overexpress PD‐L1, incorporate bioorthogonal cell surface tags, and load rapamycin for sustained release.
Yihui Wang +14 more
wiley +1 more source
The Fishes of Chadron Creek, Dawes County, Nebraska [PDF]
, 2017 This first modern comprehensive survey of fishes collected from Chadron Creek, Dawes County, Nebraska, documents collections made with a small seine and backpack electrofisher during November 2007 and February and March 2008.
Leite, Michael B. +2 more
core +3 more sources
Advanced Science, EarlyView.In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen +15 more
wiley +1 more source
Revista de Biología Tropical, 2011 Hoplias malabaricus is a viable economic alternative for artisanal fishermen who used to live on the banks of rivers that now are dammed in Brazil. In order to preserve the species’ natural stock, the main objectives of this study were to obtain bio ...
José Luís Costa Novaes +1 more
doaj +2 more sources
Studies of Birds and Mammals in the Baird and Schwatka Mountains, Alaska [PDF]
, 1974 In 1963 a joint University of Alaska-Smithsonian Institution crew worked at five locations in the Baird and Schwatka mountains in northwestern Alaska, conducting an ecological reconnaissance and faunal and floral inventory.
Chesemore, David L., Dean, Frederick C.
core
Species-specific Real Time-PCR primers/probe systems to identify fish parasites of the genera Anisakis, Pseudoterranova and Hysterothylacium (Nematoda: Ascaridoidea) [PDF]
, 2018 Ascaridoid nematodes belonging to the genera Anisakis and Pseudoterranova are heteroxenous parasites, involving marine mammals as definitive hosts in their life-cycles, whereas crustaceans (krill), fish and squids acting as intermediate/paratenic hosts.
Colantoni, Alessandra +5 more
core +1 more source
Advanced Science, EarlyView.This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao +10 more
wiley +1 more source
Pesquisa Brasileira em Odontopediatria e Clínica IntegradaObjective: To classify samples based on caries lesions, restorations, and structural anomalies to facilitate research sample selection and analyze potential oral health patterns.
Gabriela Ferreira +5 more
doaj