Results 91 to 100 of about 29,478,974 (394)
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Automated Calibration of SWMM for Improved Stormwater Model Development and Application
HydrologyThe fast pace of urban development and increasing intensity of precipitation events have made managing urban stormwater an increasingly difficult challenge.
Hossein Ahmadi +3 more
doaj +1 more source
Renal Replacement Therapy, 2020 Background Catheter-related infection of peritoneal dialysis (PD) is one of the serious factors of peritonitis. However, an antibacterial PD catheter has not been commercially available in Japan yet.
Hiroki Gyotoku +2 more
doaj +1 more source
Dynamic model for failures in biological systems [PDF]
, 2005 A dynamic model for failures in biological organisms is proposed and studied both analytically and numerically. Each cell in the organism becomes dead under sufficiently strong stress, and is then allowed to be healed with some probability.
+7 more
core +1 more source
Inferring catalysis in biological systems
IET Systems Biology, 2016 In systems biology, one is often interested in the communication patterns between several species, such as genes, enzymes or proteins. These patterns become more recognisable when temporal experiments are performed. This temporal communication can be structured by reaction networks such as gene regulatory networks or signalling pathways.
Kondofersky, I., Theis, F.J., Fuchs, C.
openaire +5 more sources
The importance of boron in biological systems [PDF]
Journal of Trace Elements in Medicine and Biology, 2018 Boron is an essential element for plants and probably essential for human and animal health. Boron has a broad range of physiological effects on biological systems at low concentrations, whereas it is toxic to at high concentrations. Eventhough there are many studies on boron's biological effects and toxicity, more information is needed to understand ...
Uluisik, Irem +2 more
openaire +5 more sources
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Predicting biological system objectives de novo from internal state measurements
BMC Bioinformatics, 2008 BackgroundOptimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For example, methods are emerging to engineer cells to optimally produce byproducts of
Erwin P. Gianchandani +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Photoactivated biological processes as quantum measurements. [PDF]
, 2015 We outline a framework for describing photoactivated biological reactions as generalized quantum measurements of external fields, for which the biological system takes on the role of a quantum meter.
Imamoglu, A, Whaley, KB
core +1 more source