Results 121 to 130 of about 6,047,039 (310)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1965
, 1966 Annual report of the Marine Biological Laboratory in Woods Hole. 1965.
Marine Biological Laboratory (Woods Hole MA)
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1944
, 1945 Annual report of the Marine Biological Laboratory in Woods Hole. 1944.
Marine Biological Laboratory (Woods Hole MA)
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1910
, 1911 Annual report of the Marine Biological Laboratory in Woods Hole. 1910.
Marine Biological Laboratory (Woods Hole MA)
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Patient Preference and Adherence, 2018 Rob Horne,1 Adelin Albert,2 Caroline Boone3 1University College London School of Pharmacy, London, UK; 2Biostatistics, University Hospital of Liége, Liége, Belgium; 3Medical Department, Pfizer SA/NV, Brussels, Belgium Objective: In ...
Horne R, Albert A, Boone C
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source