Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1986
Annual report of the Marine Biological Laboratory in Woods Hole. 1986.
Marine Biological Laboratory (Woods Hole MA)
core
Proactive Tight Monitoring of Patients with Inflammatory Bowel Disease in Biological Therapy: A Controlled Clinical Study (TIME IT). [PDF]
Christensen KR +6 more
europepmc +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1918
Annual report of the Marine Biological Laboratory in Woods Hole. 1918.
Marine Biological Laboratory (Woods Hole MA)
core
The Use of High-Frequency Skin Ultrasound in the Evaluation of Psoriatic Plaques-A Pilot Comparative Study Between Conventional and Biological Therapy. [PDF]
Ghilencea AF +4 more
europepmc +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1924
Annual report of the Marine Biological Laboratory in Woods Hole. 1924.
Marine Biological Laboratory (Woods Hole MA)
core
An Evaluation of Factors Contributing to Primary Nonresponse to Biological Therapy in Patients with Spondyloarthropathy: A Retrospective Cohort Study. [PDF]
Oğuz Kökoğlu E +5 more
europepmc +1 more source

