Results 161 to 170 of about 5,744,468 (268)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1926

, 1927
Annual report of the Marine Biological Laboratory in Woods Hole. 1926.
Marine Biological Laboratory (Woods Hole MA)
core  

Colonic biopsy-associated microbial signatures are predictive of response to anti-TNFα biological therapy in Crohn's disease. [PDF]

Front Cell Infect Microbiol
Zafeiropoulou K, Hageman IL, Mu T, Davids M, Li Yim AYF, Joustra VW, Hakvoort TBM, Satsangi J, Chronas K, Koelink PJ, Wildenberg ME, van den Wijngaard RM, D'Haens GR, de Jonge WJ.   +13 more
europepmc   +1 more source

Combination of Biological Therapy in Severe Asthma: Where We Are? [PDF]

J Pers Med, 2023
Carriera L, Fantò M, Martini A, D'Abramo A, Puzio G, Scaramozzino MU, Coppola A.   +6 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1948

, 1948
Annual report of the Marine Biological Laboratory in Woods Hole. 1948.
Marine Biological Laboratory (Woods Hole MA)
core  

Latin American consensus on tapering of biological therapy in psoriasis. [PDF]

An Bras Dermatol
Londoño-García AM, Castro-Ayarza JR, Franco Franco MD, González Ardila CF, Magariños G, Rivas Zaldívar ES, Martínez S, Ibatá L, Castillo JC, Cárdenas Rojas PJ, Castro Vargas EG, Contreras CR, de la Cruz Fernández C, Chavarriaga Restrepo A, Echeverria CM, Esteves de Carvalho AV, Hidalgo Matlock B, Loayza E, Maskin MR, Romiti R, Valenzuela F.   +20 more
europepmc   +1 more source

Correction to: Aptamer-Functionalized Fluorescent Silica Nanoparticles for Highly Sensitive Detection of Leukemia Cells

Discover Nano
Juntao Tan, Nuo Yang, Zixi Hu, Jing Su, Jianhong Zhong, Yang Yang, Yating Yu, Jianmeng Zhu, Dabin Xue, Yingying Huang, Zongqiang Lai, Yong Huang, Xiaoling Lu, Yongxiang Zhao   +13 more
doaj   +1 more source

Corrigendum: Regulatory Framework for Advanced Therapy Medicinal Products in Europe and United States

Frontiers in Pharmacology, 2020
Carolina Iglesias-Lopez, Antonia Agustí, Antonia Agustí, Mercè Obach, Antonio Vallano, Antonio Vallano   +5 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source