Results 151 to 160 of about 6,047,039 (310)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1930

, 1931
Annual report of the Marine Biological Laboratory in Woods Hole. 1930.
Marine Biological Laboratory (Woods Hole MA)
core  

The Use of High-Frequency Skin Ultrasound in the Evaluation of Psoriatic Plaques-A Pilot Comparative Study Between Conventional and Biological Therapy. [PDF]

J Imaging
Ghilencea AF, Costache DO, Căruntu C, Moga M, Costache RS.   +4 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1945

, 1946
Annual report of the Marine Biological Laboratory in Woods Hole. 1945.
Marine Biological Laboratory (Woods Hole MA)
core  

An Evaluation of Factors Contributing to Primary Nonresponse to Biological Therapy in Patients with Spondyloarthropathy: A Retrospective Cohort Study. [PDF]

Arch Rheumatol
Oğuz Kökoğlu E, Kaplan H, Kızıltepe M, Kahraman Denizhan T, Cengiz CB, Şenel AS.   +5 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1957

, 1957
Annual report of the Marine Biological Laboratory in Woods Hole. 1957.
Marine Biological Laboratory (Woods Hole MA)
core  

Author Correction: Fusions of Tumor-derived Endothelial Cells with Dendritic Cells Induces Antitumor Immunity

Scientific Reports
Yingying Huang, Qiqi Mao, Jian He, Jing Su, Yi Peng, Wei Liang, Zixi Hu, Sufang Zhou, Xiaoling Lu, Yongxiang Zhao   +9 more
doaj   +1 more source

Exploratory Retrospective Assessment of Patients with Psoriasis Receiving Biological Therapy. [PDF]

Medicina (Kaunas)
Lazar AL, Bolboacă SD, Baican AL, Baican CI, Dănescu S, Candrea E, Câmpean DV, Iluț P, Semenescu I, Sitar-Tăut AV, Vulturar R, Orășan OH, Cozma A.   +12 more
europepmc   +1 more source