Results 151 to 160 of about 5,744,468 (268)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1957

, 1957
Annual report of the Marine Biological Laboratory in Woods Hole. 1957.
Marine Biological Laboratory (Woods Hole MA)
core  

Exploratory Retrospective Assessment of Patients with Psoriasis Receiving Biological Therapy. [PDF]

Medicina (Kaunas)
Lazar AL, Bolboacă SD, Baican AL, Baican CI, Dănescu S, Candrea E, Câmpean DV, Iluț P, Semenescu I, Sitar-Tăut AV, Vulturar R, Orășan OH, Cozma A.   +12 more
europepmc   +1 more source

Author Correction: Fusions of Tumor-derived Endothelial Cells with Dendritic Cells Induces Antitumor Immunity

Scientific Reports
Yingying Huang, Qiqi Mao, Jian He, Jing Su, Yi Peng, Wei Liang, Zixi Hu, Sufang Zhou, Xiaoling Lu, Yongxiang Zhao   +9 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1896-1902

, 1902
Annual report of the Marine Biological Laboratory in Woods Hole for the years 1896-1899.
Marine Biological Laboratory (Woods Hole MA)
core  

Biological Therapy for Moderate-to-Severe Psoriasis: A 5-Year Analysis of Patients from Lithuania. [PDF]

Medicina (Kaunas)
Indrisiunaite E, Jonaityte IR, Karmaziene T, Raudonis T.   +3 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1967

, 1968
Annual report of the Marine Biological Laboratory in Woods Hole. 1967.
Marine Biological Laboratory (Woods Hole MA)
core  

Incidence of tuberculosis in patients with immune-mediated diseases undergone biological therapy: A 10-year observational study in a high-burden region of northeastern Brazil. [PDF]

PLoS One
Dos Santos Guimarães RM, Lopes Marques CD, Montarroyos UR, Guimarães CS, Alves da Silva J, Filho LFS, Medeiros V, de Aquino IRPUC, Dhalia R, Lopes EP, Brito CAA.   +10 more
europepmc   +1 more source