Results 171 to 180 of about 1,154,039 (314)

Author Correction: Fusions of Tumor-derived Endothelial Cells with Dendritic Cells Induces Antitumor Immunity

open access: yesScientific Reports
Yingying Huang   +9 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Latin American consensus on tapering of biological therapy in psoriasis. [PDF]

open access: yesAn Bras Dermatol
Londoño-García AM   +20 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Initial Treatment with Biological Therapy in Rheumatoid Arthritis. [PDF]

open access: yesJ Clin Med, 2023
Tornero Molina J   +2 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Impact of SARS-CoV-2 on Severe Asthma Patients Undergoing Biological Therapy: A Multicenter Study. [PDF]

open access: yesJ Clin Med
Lampalo M   +15 more
europepmc   +1 more source

CONTEMPORARY THERAPY WITH BIOLOGICAL DRUGS

open access: yes, 2018
Biološka terapija uključuje uporabu živih organizama, tvari koje potječu od živih organizama ili laboratorijskih verzija takvih supstancija za liječenje bolesti. Osnovna primjena biološke terapije identificirana je za širok spektar bolesti.
Radolović Raljević, Marina
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