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The synthesis and biological evaluation of dopamine transporter inhibiting activity of substituted diphenylmethoxypiperidines

Bioorganic & Medicinal Chemistry Letters, 2005
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Gennady B, Lapa   +6 more
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Experimental evidence and biological significance of active transport

1961
All living organisms as well as the individual cells of which they are composed are faced by two problems which are obviously antagonistic: They must retain their integrity, constraining their component molecules within a definite space, but, at the same time, require a continuous or periodic exchange of molecules with their surroundings. Off-hand, the
openaire   +1 more source

Protein kinase C activation increases transepithelial transport of biologically active insulin.

Cancer research, 1998
Protein kinase C activation leads to tight junctional leakiness and, consequently, to increased transepithelial (paracellular) solute flux across epithelial barriers. This leakiness is shown here to result in as much as a 20-fold increase in the transepithelial flux of insulin.
J M, Mullin, N, Ginanni, K V, Laughlin
openaire   +1 more source

Biological transport in a microfabricated device: active immunochromatography with motorized antibodies

SPIE Proceedings, 1998
Kinesin motor proteins transduce chemical energy released by adenosine triphosphate hydrolysis into mechanical force and motion along microtubule tracks. Biological cells use kinesin motors to transport intracellular components to specific cellular locations.
Loren Limberis, Russell J. Stewart
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Stochastic modeling of active biological transport in inhomogeneous environments

2010
Diese Arbeit behandelt Systeme aktiv getriebener Teilchen auf gerichteten Pfaden in inhomogenen Umgebungen. Ein Beispiel ist Straßenverkehr. Hauptgesichtspunkt ist jedoch die Modellierung gerichteter kollektiver Bewegung von molekularen Motoren bei Proteinproduktion oder Transport auf intrazellulären Filamenten.
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Saponins in Calendula officinalis L. – Structure, Biosynthesis, Transport and Biological Activity

Phytochemistry Reviews, 2005
Trends in research on Calendula officinalis L. saponins performed in Department of Plant Biochemistry at Warsaw University are reviewed. Calendula officinalis, a well known medicinal plant, contains significant amounts of oleanane saponins, which form two distinct series of related compounds, called “glucosides” and “glucuronides” according to the ...
Anna Szakiel   +2 more
openaire   +1 more source

[Variability of biological glucose transport activity in human erythrocytes].

Comptes rendus des seances de la Societe de biologie et de ses filiales, 1992
Glucose transport activity was determined on erythrocytes from healthy adult and children. A large variability of values was found between each donor, but transport rate was significantly higher in erythrocytes from adults than those from children. In opposite, the same number of glucose transport sites was found on erythrocytes from adult and children,
J P, Feugeas   +3 more
openaire   +1 more source

Active Ionic Transport across Biological Membranes: Possible Role of Electrons and Protons

Nature, 1970
THE conversion of metabolic energy into useful work is a very efficient process in biological cells. The energy in ATP is transformed into mechanical, electrical and osmotic work at efficiencies which have been calculated to approach 100 per cent for acid secretion in the stomach1, active Na+ transport in frog skin2 and sartorius muscle contraction3 ...
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Active transport across biological membranes : quantification and limits

Caco-2/MDCK assays are key tools for assessing compound permeability and active transport. The efflux ratio (ER) is often used to infer active efflux, but cannot be used as a direct measure of active transport. This work probes the viability of using intrinsic values to quantify efflux by extending existing models to incorporate aqueous boundary layers
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ACTIVE TRANSPORT OF CATIONS ACROSS BIOLOGICAL MEMBRANES

Annals of the New York Academy of Sciences, 1974
W D, Stein, Y, Eilam, W R, Lieb
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