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Exosomes: Generation, structure, transport, biological activity, and diagnostic application
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology, 2016Cells of almost all tissues secrete to the extracellular environment a variety of vesicular structures. The most interesting vesicles are exosomes–microvesicles ranging from 30 to 100 nm in size. These vesicles contain various RNA, including mRNA, microRNA, as well as membrane and cytoplasmic proteins that can be transported in these particles to ...
S. N. Tamkovich +2 more
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SPIE Proceedings, 1998
Kinesin motor proteins transduce chemical energy released by adenosine triphosphate hydrolysis into mechanical force and motion along microtubule tracks. Biological cells use kinesin motors to transport intracellular components to specific cellular locations.
Loren Limberis, Russell J. Stewart
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Kinesin motor proteins transduce chemical energy released by adenosine triphosphate hydrolysis into mechanical force and motion along microtubule tracks. Biological cells use kinesin motors to transport intracellular components to specific cellular locations.
Loren Limberis, Russell J. Stewart
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Noise-stimulated active transport in biological cell membranes
Physics Letters A, 1994Abstract We show that existing experimental data on active transport of ions in living biological cells can be interpreted in terms of the transfer of energy from the stochastic field (fluctuations of membrane potential), and propose a method of further experimental verification of this interpretation.
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The mutual binding exclusion mechanism in active transport across biological membranes
Cell Biophysics, 1987The coupling mechanism of sarcoplasmic reticulum ATPase is based on the reciprocal influence of calcium binding and phosphorylation domains. Cooperative calcium binding activates the enzyme, permitting utilization of ATP by transfer of its terminal phosphate to the enzyme.
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Stochastic modeling of active biological transport in inhomogeneous environments
2010Diese Arbeit behandelt Systeme aktiv getriebener Teilchen auf gerichteten Pfaden in inhomogenen Umgebungen. Ein Beispiel ist Straßenverkehr. Hauptgesichtspunkt ist jedoch die Modellierung gerichteter kollektiver Bewegung von molekularen Motoren bei Proteinproduktion oder Transport auf intrazellulären Filamenten.
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[Variability of biological glucose transport activity in human erythrocytes].
Comptes rendus des seances de la Societe de biologie et de ses filiales, 1992Glucose transport activity was determined on erythrocytes from healthy adult and children. A large variability of values was found between each donor, but transport rate was significantly higher in erythrocytes from adults than those from children. In opposite, the same number of glucose transport sites was found on erythrocytes from adult and children,
J P, Feugeas +3 more
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Protein kinase C activation increases transepithelial transport of biologically active insulin.
Cancer research, 1998Protein kinase C activation leads to tight junctional leakiness and, consequently, to increased transepithelial (paracellular) solute flux across epithelial barriers. This leakiness is shown here to result in as much as a 20-fold increase in the transepithelial flux of insulin.
J M, Mullin, N, Ginanni, K V, Laughlin
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ACTIVE TRANSPORT OF CATIONS ACROSS BIOLOGICAL MEMBRANES
Annals of the New York Academy of Sciences, 1974W D, Stein, Y, Eilam, W R, Lieb
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Active transport across biological membranes : quantification and limits
Caco-2/MDCK assays are key tools for assessing compound permeability and active transport. The efflux ratio (ER) is often used to infer active efflux, but cannot be used as a direct measure of active transport. This work probes the viability of using intrinsic values to quantify efflux by extending existing models to incorporate aqueous boundary layersopenaire +1 more source