Results 231 to 240 of about 6,267,247 (357)
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Case Studies in Thermal EngineeringComplex cilia waves have diverse applications in physiological flow transport across various biological systems. This study presents a novel investigation into the effects of electroosmosis in a non-uniform channel lined with cilia for an Eyring-Powell ...
Abaker A. Hassaballa +3 more
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Flexible thin-film thermal sensor for estimating thermal transport properties designed for biomaterial applications. [PDF]
Sci RepOkabe T, Shiroto A, Hiyama Y, Taguchi K.
europepmc +1 more source
Mineralogical comparisons of experimental results investigating the biological impacts on rock transport processes [PDF]
, 2013 Doris Wagner +4 more
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
The Dynamics of Cell-to-Cell Water Transport and the Involvement of Aquaporins in Response to Apoplast Blockage in the Roots of Intact Maize Plants. [PDF]
CellsSuslov M.
europepmc +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Temporal dynamics of gene expression during the development of <i>Campylobacter jejuni</i> biofilms. [PDF]
Microb GenomVolk M, Gundogdu O, Klančnik A.
europepmc +1 more source