Results 241 to 250 of about 6,267,247 (357)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Adaptive Evolution of GatC, a Component of the Galactitol Phosphotransferase System, for Glucose Transport in <i>Escherichia coli</i>. [PDF]

J Microbiol Biotechnol
Jeong SO, Kim HJ, Lee SJ.
europepmc   +1 more source

S3e2-2 Membrane Traffic : Elaborate Transport Systems within a Cell(S3-e2: "Molecular Communication: Biologically Inspired Communication Systems for Nano-Scale Devices",Symposia,Abstract,Meeting Program of EABS & BSJ 2006)

, 2006
Akihiko Nakano, Ken Sato
openalex   +2 more sources

Sample handling in surface sensitive chemical and biological sensing: A practical review of basic fluidics and analyte transport [PDF]

, 2014
Norbert Orgován, Dániel Patkó, Csaba Hős, Sándor Kurunczi, Bálint Szabó, Jeremy J. Ramsden, Róbert Horváth   +6 more
openalex   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Laser driven FLASH radiobiology using a high dose and ultra high dose rate single pulse proton source. [PDF]

Sci Rep
Flacco A, Bayart E, Romagnani L, Cavallone M, De Marzi L, Fouillade C, Giaccaglia C, Heinrich S, Lamarre-Jouenne I, Monzac J, Parodi K, Patriarca A, Rösch T, Schreiber J, Tischendorf L.   +14 more
europepmc   +1 more source

BioFVM: an efficient, parallelized diffusive transport solver for 3-D biological simulations [PDF]

, 2015
Ahmadreza Ghaffarizadeh, Samuel H. Friedman, Paul Macklin   +2 more
openalex   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Directional Liquid Transport on Biomimetic Surface with Wedge-Shaped Pattern: Mechanism, Construction, and Applications. [PDF]

Biomimetics (Basel)
Meng Q, Zhou J, Pang J, Wang L, Yang K, Li Z, Xie J.   +6 more
europepmc   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source