Results 21 to 30 of about 6,293,770 (377)

Emerging Roles of γ Aminobutyric Acid (GABA) Gated Channels in Plant Stress Tolerance

Plants, 2021
The signaling role for γ-Aminobutyric acid (GABA) has been documented in animals for over seven decades. However, a signaling role for GABA in plants is just beginning to emerge with the discovery of putative GABA binding site/s and GABA regulation of ...
Mona Kaspal, Madhuka H. Kanapaddalagamage, Sunita A. Ramesh   +2 more
doaj   +1 more source

An Interspecies Molecular and Functional Study of Organic Cation Transporters at the Blood-Brain Barrier: From Rodents to Humans

Pharmaceutics, 2020
Organic cation transporters (OCTs) participate in the handling of compounds in kidneys and at the synaptic cleft. Their role at the blood-brain barrier (BBB) in brain drug delivery is still unclear.
Catarina Chaves, Federica Campanelli, Hélène Chapy, David Gomez-Zepeda, Fabienne Glacial, Maria Smirnova, Meryam Taghi, Johan Pallud, Nicolas Perrière, Xavier Declèves, Marie-Claude Menet, Salvatore Cisternino   +11 more
doaj   +1 more source

Rescue of dendritic cells from glycolysis inhibition improves cancer immunotherapy in mice

Nature Communications, 2023
Inhibition of glycolysis in immune cells and cancer cells diminishes their activity, and thus combining immunotherapies with glycolytic inhibitors is challenging.
Sahil Inamdar, Abhirami P. Suresh, Joslyn L. Mangal, Nathan D. Ng, Alison Sundem, Christopher Wu, Kelly Lintecum, Abhirami Thumsi, Taravat Khodaei, Michelle Halim, Nicole Appel, Madhan Mohan Chandra Sekhar Jaggarapu, Arezoo Esrafili, Jordan R. Yaron, Marion Curtis, Abhinav P. Acharya   +15 more
doaj   +1 more source

Advances of Commercial and Biological Materials for Electron Transport Layers in Biological Applications

Frontiers in Bioengineering and Biotechnology, 2022
Electron transport layer (ETL), one of the important layers for high-performing perovskite solar cells (PSCs), also has great potential in bioengineering applications. It could be used for biological sensors, biological imaging, and biomedical treatments
Zhifu Yin, Zhifu Yin, Biao Lu, Yanbo Chen, Caixia Guo   +4 more
doaj   +1 more source

Effects of Polymer 3D Architecture, Size, and Chemistry on Biological Transport and Drug Delivery In Vitro and in Orthotopic Triple Negative Breast Cancer Models

Advanced Healthcare Materials, 2020
The size, shape, and underlying chemistries of drug delivery particles are key parameters which govern their ultimate performance in vivo. Responsive particles are desirable for triggered drug delivery, achievable through architecture change and ...
Amanda K. Pearce, Akosua B. Anane‐Adjei, R. Cavanagh, P. Monteiro, Thomas M. Bennett, Vincenzo Taresco, P. Clarke, A. Ritchie, M. Alexander, A. Grabowska, C. Alexander   +10 more
semanticscholar   +1 more source

Dual-Task Performance in Hearing-Impaired Older Adults—Study Protocol for a Cross-Sectional Mobile Brain/Body Imaging Study

Frontiers in Aging Neuroscience, 2021
Background: Hearing impairments are associated with reduced walking performance under Dual-task (DT) conditions. Little is known about the neural representation of DT performance while walking in this target group compared to healthy controls or younger ...
Anna Wunderlich, Oliver Vogel, Maja Maša Šömen, Manca Peskar, Manca Peskar, Madeleine Fricke, Klaus Gramann, Janna Protzak, Uros Marusic, Uros Marusic, Bettina Wollesen, Bettina Wollesen   +11 more
doaj   +1 more source

Temporal evaluation of efficacy and quality of tissue repair upon laser‐activated sealing

Bioengineering & Translational Medicine, 2023
Injuries caused by surgical incisions or traumatic lacerations compromise the structural and functional integrity of skin. Immediate approximation and robust repair of skin are critical to minimize occurrences of dehiscence and infection that can lead to
Deepanjan Ghosh, Christopher M. Salinas, Shubham Pallod, Jordan Roberts, Inder Raj S. Makin, Jordan R. Yaron, Russell S. Witte, Kaushal Rege   +7 more
doaj   +1 more source

Oral drug delivery for immunoengineering

Bioengineering & Translational Medicine, 2022
The systemic pharmacotherapeutic efficacy of immunomodulatory drugs is heavily influenced by its route of administration. A few common routes for the systemic delivery of immunotherapeutics are intravenous, intraperitoneal, and intramuscular injections ...
Tien Le, Brian Aguilar, Joslyn L. Mangal, Abhinav P. Acharya   +3 more
doaj   +1 more source

Permeability of the Perindopril Arginine under In Vitro Conditions across Caco-2 Monolayer and Biomimetic Phospholipid Membrane

Molecules, 2022
Perindopril arginine (PA) as an angiotensin-converting enzyme (ACE) inhibitor is widely used in cardiovascular diseases, especially in systemic hypertension and heart failure. Although the pharmacokinetics of PA are well documented, there is no available
Marta Kus, Klaudia Gorniak, Piotr Czaklosz, Anna Olejnik, Paulina Skupin-Mrugalska, Izabela Ibragimow, Hanna Piotrowska-Kempisty   +6 more
doaj   +1 more source

Interfacial and Internal Proton Conduction of Weak-acid Functionalized Styrene-based Copolymer with Various Carboxylic Acid Concentrations

Electrochemistry, 2021
Investigation of interfacial proton transport is necessary to elucidate biological systems. As commonly found in biomaterials, the carboxylic acid group was proven to act as a proton-conducting group.
Athchaya SUWANSOONTORN, Katsuhiro YAMAMOTO, Shusaku NAGANO, Jun MATSUI, Yuki NAGAO   +4 more
doaj   +1 more source