Results 21 to 30 of about 12,619 (163)

P20 Potentiel antibactérien de l’huile essentielle d’Ocimum gratissimum sur des entérobactéries isolées de diverses infections.

Journal Africain de Technologie Pharmaceutique et Biopharmacie, 2023
Les échecs thérapeutiques dus à l’antibiorésistance bactérienne pose un problème majeur de santé publique. Parmi les solutions qui s’offrent, les plantes médicinales constituent une bonne alternative.
C Avide Ahouansou, G alida Oussou, Sedami Medegan Faglan , Victorien T Dougnon, Fernand A Gbaguidi   +4 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

L´arthrite tuberculeuse isolée du genou, un diagnostic difficile chez l'adolescent: rapport de cas

The Pan African Medical Journal, 2020
La tuberculose est un problème majeur de santé publique au niveau mondiale. La forme ostéo-articulaire est rarissime, elle est dominé par la localisation vertébrale dans la moitié des cas.
Rachid Benchanna, Amine Benjelloune, Zidane abdelafatah, Adil Arsalane, Hicham Janah, Jamal Oujaber, Meriem Boui, Ikram samri, Rachid Bouchentouf   +8 more
doaj   +1 more source

Exemple d’approche fonctionnelle : le gras intramusculaire chez le porc

INRAE Productions Animales, 2020
Nous avons utilisé alternativement les techniques d’analyse fonctionnelle, d’analyse génétique et de biologie moléculaire pour identifier les gènes qui ont un effet majeur sur le gras intramusculaire du porc indépendamment de ceux qui agissent sur l ...
C. RENARD, J. MOUROT
doaj   +1 more source

The ESCRT-III isoforms CHMP2A and CHMP2B display different effects on membranes upon polymerization

BMC Biology, 2021
Background ESCRT-III proteins are involved in many membrane remodeling processes including multivesicular body biogenesis as first discovered in yeast.
Maryam Alqabandi, Nicola de Franceschi, Sourav Maity, Nolwenn Miguet, Marta Bally, Wouter H. Roos, Winfried Weissenhorn, Patricia Bassereau, Stéphanie Mangenot   +8 more
doaj   +1 more source

Cellularized Skin Substitute Bioengineering for Regenerative Medicine: Cell Sources, Culture Strategies, and Transition Toward Defined, Xeno‐Free Culture Systems

Advanced Healthcare Materials, EarlyView.
Advances in cell sources, bioengineering, and manufacturing are reshaping the design of skin substitutes. This review highlights emerging strategies driving skin tissue engineering and discusses their potential to enable safer, reproducible, and clinically accessible skin substitutes for regenerative medicine.
Gilles Lemaître, Marina Trouillas, Tatiana Vinasco‐Sandoval, Cécile Giordano, Alexandre G. Lellouch, Walid Rachidi, Jean‐Jacques Lataillade, Nicolas O. Fortunel   +7 more
wiley   +1 more source

Mise en évidence de la reproduction naturelle du saumon atlantique (Salmo salar L.) dans un affluent français du Rhin par analyse génétique d'oeufs prélevés dans des frayères

Knowledge and Management of Aquatic Ecosystems, 1996
En utilisant la réaction de polymérisation en chaîne, nous avons pu amplifier des régions spécifiques des ADN nucléaire (région conservée des gènes du rARN 5S) et mitochondrial (région ND-5/6) extraits d'oeufs prélevés sur quatre frayères de salmonidés ...
LARGIADER C. R., GUYOMARD R., ROCHE P.
doaj   +1 more source

Age-related and disease locus-specific mechanisms contribute to early remodelling of chromatin structure in Huntington’s disease mice

Nature Communications, 2021
The dynamics of chromatin and transcriptional changes underlying Huntington’s disease remain poorly understood. Here the authors use a Huntington’s mouse model to profile the striatal chromatin landscape, finding that the Huntington’s mutation ...
Rafael Alcalá-Vida, Jonathan Seguin, Caroline Lotz, Anne M. Molitor, Ibai Irastorza-Azcarate, Ali Awada, Nezih Karasu, Aurélie Bombardier, Brigitte Cosquer, Jose Luis Gomez Skarmeta, Jean-Christophe Cassel, Anne-Laurence Boutillier, Thomas Sexton, Karine Merienne   +13 more
doaj   +1 more source

Extreme Gradient Boosting Tuned with Metaheuristic Algorithms for Predicting Myeloid NGS Onco-Somatic Variant Pathogenicity

Bioengineering, 2023
The advent of next-generation sequencing (NGS) technologies has revolutionized the field of bioinformatics and genomics, particularly in the area of onco-somatic genetics.
Eric Pellegrino, Clara Camilla, Norman Abbou, Nathalie Beaufils, Christel Pissier, Jean Gabert, Isabelle Nanni-Metellus, L’Houcine Ouafik   +7 more
doaj   +1 more source

Oxidative Generation and Reactivity of the Cyclopropyl Radical From a Martin Silicate

Chemistry – A European Journal, EarlyView.
A photoredox strategy employing Martin silicates enables the oxidative generation and controlled capture of cyclopropyl radicals, including the naked one, long considered challenging intermediates. The method affords functionalized cyclopropanes through both Giese‐type additions and dual nickel/photoredox C(sp3)−C(sp2) cross‐couplings.
Amal Lakhal, Alexandre Millanvois, Louis Fensterbank, Cyril Ollivier   +3 more
wiley   +1 more source