Computational Systems Biology [PDF]
The Scientific World Journal, 2013 The complex biological systems consist of distinct molecules that exert their functions by interacting with each other, which makes it a big challenge to understand how the cellular machinery works. Recently, the accumulation of a large amount of multiscale omics data, such as next-generation sequencing data and protein interaction data, provides ...
Xing-Ming Zhao +3 more
openaire +3 more sources
Structural Biology in the Clouds: The WeNMR-EOSC Ecosystem [PDF]
Frontiers in Molecular Biosciences, 2021 Structural biology aims at characterizing the structural and dynamic properties of biological macromolecules at atomic details. Gaining insight into three dimensional structures of biomolecules and their interactions is critical for understanding the ...
R. Honorato +7 more
semanticscholar +1 more source
ProtTrans: Towards Cracking the Language of Life’s Code Through Self-Supervised Deep Learning and High Performance Computing [PDF]
bioRxiv, 2020 Computational biology and bioinformatics provide vast data gold-mines from protein sequences, ideal for Language Models (LMs) taken from Natural Language Processing (NLP). These LMs reach for new prediction frontiers at low inference costs.
Ahmed Elnaggar +11 more
semanticscholar +1 more source
The state of quantum computing applications in health and medicine [PDF]
Research Directions: Quantum Technologies, 2023 Quantum computing hardware and software have made enormous strides over the last years1. Questions around quantum computing’s impact on research and society have changed from “if” to “when/how”.
Frederik F. Flöther
semanticscholar +1 more source
Automating Fault Tolerance in High-Performance Computational Biological Jobs Using Multi-Agent Approaches [PDF]
, 2014 Background: Large-scale biological jobs on high-performance computing systems require manual intervention if one or more computing cores on which they execute fail.
Alexandrov, Vassil +2 more
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Measurement of insect mass based on ellipsoid scattering model
The Journal of Engineering, 2019 Insect migration influences population dynamics, provides ecosystem services, causes heavy crop damages and spreads diseases. The identification of insect migrants is critically important for the study of insect migration.
Shaoyang Kong +3 more
doaj +1 more source
MiRNA‐145‐5p expression and prospective molecular mechanisms in the metastasis of prostate cancer
IET Systems Biology, 2021 The clinicopathological implication and prospective molecular mechanisms of miRNA‐145‐5p in the metastasis of prostate cancer (PCa) stand unclear. Herein, it is found that miRNA‐145‐5p expression was remarkably reduced in 131 cases of metastatic PCa than
Zhi‐Guang Huang +8 more
doaj +1 more source
Engineering biology: a key driver of the bio-economy
Engineering Biology, 2017 This study provides a relatively brief overview of the field of synthetic biology/engineering biology for the non-specialist reader. This is in line with one of the basic aims of the new journal Engineering Biology – which is to open up the field to a ...
Richard I. Kitney, Paul S. Freemont
doaj +1 more source
Engineered gene networks enable non-genetic drug resistance and enhanced cellular robustness
Engineering Biology, 2019 Drug resistance complicates the treatment of cancer and infectious diseases, and often arises from the elevated expression of a gene that neutralises or reduces drug activity.
Brendan Camellato +6 more
doaj +1 more source
Short-term synaptic plasticity in emerging devices for neuromorphic computing
iScience, 2023 Summary Neuromorphic computing is a promising computing paradigm toward building next-generation artificial intelligence machines, in which diverse types of synaptic plasticity play an active role in information processing.
Chao Li +9 more
semanticscholar +1 more source