Results 151 to 160 of about 1,431,950 (311)

The Metamorphosing Professor: Adapting Teaching to Fulfill the Promise of Biology Education. [PDF]

Integr Comp Biol, 2022
García-Ojeda ME, Nishiguchi MK.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Correction: Integrating tropical research into biology education is urgently needed. [PDF]

PLoS Biol, 2022
Russell AE, Aide TM, Braker E, Bruno EM, Ganong CN, Hardin RD, Holl KD, Hotchkiss SC, Klemens JA, Kuprewicz EK, McClearn D, Middendorf G, Ostertag R, Powers JS, Russo SE, Stynoski JL, Valdez U, Willis CG.   +17 more
europepmc   +1 more source

‘Thoughtfulness’ in Biology Education [PDF]

The Biochemist, 2017
openaire   +2 more sources

Global Climate Change: Impact and Remediation [PDF]

This "clicker case" is a continuation of another case study "Global Climate Change: Evidence and Causes". Students assume the role of an intern working for a U.S.
Maureen Knabb, Timothy Lutz
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Basic biology education in high school and acceptance of genetically modified food in Japan. [PDF]

PLoS One, 2023
Mine A, Okamoto S, Myojin T, Hamada M, Imamura T.   +4 more
europepmc   +1 more source

Standards for the Ph.D. Degree in the Molecular Biosciences [PDF]

, 2000
The International Union of Biochemistry and Molecular Biology, Committee on Education,
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

GENETİK KONUSUNA AİT KAVRAMLARIN FARKLI ÖĞRENCİ SEVİYELERİNE GÖRE DEĞİŞİMİ

Sakarya Üniversitesi Eğitim Fakültesi Dergisi, 2013
Kavramlar insanlarÕn düúünce sisteminde yer alan soyut birimlerdir. Bilgileri sÕnÕflandÕrmak suretiyle insanlar arasÕ iletiúimi kolaylaútÕrÕrlar. YapÕlan çalÕúmalar ö÷rencilerin bilimsel kavramlarÕ okulda ö÷renmelerine ra÷men do÷al olaylar hakkÕnda daha ...
Arzu Saka
doaj